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Total Questions : 82 | Page 8 of 9 pages
Question 71. Which of the following is untrue about FootPrinter?
  1.    It is a web-based program for phylogenetic footprinting using multiple input sequences
  2.    The motifs from organisms spanning over the widest evolutionary distances are identified as promoter or regulatory motifs
  3.    The program performs multiple alignment of the input sequences to identify conserved motifs
  4.    The user does not necessarily provides a phylogenetic tree that defines the evolutionary relationship of the input sequences
 Discuss Question
Answer: Option D. -> The user does not necessarily provides a phylogenetic tree that defines the evolutionary relationship of the input sequences
Answer: (d).The user does not necessarily provides a phylogenetic tree that defines the evolutionary relationship of the input sequences
Question 72. Which of the following is untrue about Expression Profiling–Based Method?
  1.    Genes with similar expression profiles are considered coexpressed, which can be identified through a clustering approach
  2.    This approach appears to be less effective for finding transcription factor binding sites
  3.    An advanced alignment-independent profile construction method such as EM and Gibbs motif sampling is often used in finding the subtle sequence motifs
  4.    The basis for coexpression is thought to be due to common promoters and regulatory elements
 Discuss Question
Answer: Option B. -> This approach appears to be less effective for finding transcription factor binding sites
Answer: (b).This approach appears to be less effective for finding transcription factor binding sites
Question 73. Which of the following is a wrong statement regarding the conventional determination of open reading frames?
  1.    Without the use of specialized programs, prokaryotic gene identification can rely on manual determination of ORFs and major signals related to prokaryotic genes
  2.    Prokaryotic DNA is first subject to conceptual translation in all six possible frames, two frames forward and four frames reverse
  3.    A stop codon occurs in about every twenty codons by chance in a noncoding region
  4.    Prokaryotic DNA is first subject to conceptual translation in all six possible frames, three frames forward and three frames reverse
 Discuss Question
Answer: Option B. -> Prokaryotic DNA is first subject to conceptual translation in all six possible frames, two frames forward and four frames reverse
Answer: (b).Prokaryotic DNA is first subject to conceptual translation in all six possible frames, two frames forward and four frames reverse
Question 74. There are ____ possible stop codons, identification of which is straightforward.
  1.    five
  2.    two
  3.    ten
  4.    three
 Discuss Question
Answer: Option D. -> three
Answer: (d).three
Question 75. The presence of these codons at The beginning of the frame _____ give a clear indication of the translation initiation site.
  1.    always
  2.    does not necessarily
  3.    does not
  4.    never
 Discuss Question
Answer: Option B. -> does not necessarily
Answer: (b).does not necessarily
Question 76. Shine-Delgarno sequence, which is a stretch of purine-rich sequence complementary to 16S rRNA in the ribosome.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 77. The putative ORF can be translated into a protein sequence, which is then used to search against a protein database.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 78. In bacteria, transcription is initiated by DNA polymerase.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 79. The promoter sequence may determine the expression of one gene or a number of linked genes downstream.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 80. The upstream sequence where the σ protein binds constitutes the promoter sequence.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True

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