Questions and answers for exam Preparation

MCQs

Total Questions : 82 | Page 6 of 9 pages

Question 51. Which of the following is untrue about Homology-Based Programs?

They are based on the fact that exon structures and exon sequences of related species are less conserved
This approach assumes that the database sequences are correct
It is a reasonable assumption in light of the fact that many homologous sequences to be compared with are derived from cDNA or expressed sequence tags (ESTs) of the same species
Potential coding frames in a query sequence are translated and used to align with closest protein homologs found in databases

Discuss Question

Answer: Option A. -> They are based on the fact that exon structures and exon sequences of related species are less conserved
Answer: (a).They are based on the fact that exon structures and exon sequences of related species are less conserved

Question 52. GENSCAN is awebbased program that makes predictions based on fifth-order HMMs.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 53. In eukaryotes, gene expression is not regulated by a protein complex formed between transcription factors and RNA polymerase.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 54. Which of the following is untrue?

RNA polymerases I is responsible for the transcription of ribosomal RNA
RNA polymerases III is responsible for the transcription of tRNA
RNA polymerase II is exclusively responsible for transcribing protein-encoding genes
Synthesis of mRNAs is carried out by RNA polymerase I

Discuss Question

Answer: Option D. -> Synthesis of mRNAs is carried out by RNA polymerase I
Answer: (d).Synthesis of mRNAs is carried out by RNA polymerase I

Question 55. Eukaryotic RNA polymerase II does not directly bind to the promoter, but relies on a dozen or more transcription factors to recognize and bind to the promoter in a specific order before its own binding around the promoter.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 56. The TATA box is often used as an indicator of the presence of a promoter.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 57. In eukaryotes, genes often form an operon with a shared promoter.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 58. Which of the following is incorrect regarding the Prediction for Eukaryotes?

The consensus patterns are only derived from bioinformatics studies
The experimentally determined DNA binding sites are compiled into profiles and stored in a database for scanning an unknown sequence to find similar conserved patterns
The consensus patterns are derived from experimentally determined DNA binding sites
The ab initio method for predicting eukaryotic promoters and regulatory elements relies on searching the input sequences for matching of consensus patterns of known promoters and regulatory elements

Discuss Question

Answer: Option A. -> The consensus patterns are only derived from bioinformatics studies
Answer: (a).The consensus patterns are only derived from bioinformatics studies

Question 59. CpGProD is a web-based program that predicts promoters containing a high density of CpG islands _______

in archea genomic sequences
in mammalian genomic sequences
in eukaryotic and bacterial genomic sequences
only in bacterial genomic sequences

Discuss Question

Answer: Option B. -> in mammalian genomic sequences
Answer: (b).in mammalian genomic sequences

Question 60. Which of the following is incorrect regarding Eponine?

It is a web-based program that predicts transcription start sites
It is a web-based program that particularly predicts tranpososons and retropososons
The regulatory sites include the TATA box, the CCAAT box, and CpG islands
It is based on a series of pre-constructed PSSMs of several regulatory sites

Discuss Question

Answer: Option B. -> It is a web-based program that particularly predicts tranpososons and retropososons
Answer: (b).It is a web-based program that particularly predicts tranpososons and retropososons