Questions and answers for exam Preparation

MCQs

Total Questions : 82 | Page 2 of 9 pages

Question 11. Once an operon structure is known ______ for the presence of a promoter and regulatory elements _____ in the operon do not possess such DNA elements.

only the first gene is predicted, whereas other genes
only the first hundred genes are predicted, whereas next few genes
only first two genes are predicted, whereas next few genes
only first ten genes are predicted, whereas next few genes

Discuss Question

Answer: Option A. -> only the first gene is predicted, whereas other genes
Answer: (a).only the first gene is predicted, whereas other genes

Question 12. In BPROM, once the operons are assigned, the program is able to predict putative promoter sequences.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 13. Which of the following is incorrect regarding FindTerm?

It is a program for searching bacterial ρ-independent termination signals located at the end of operons
It is a program for searching bacterial ρ-dependent termination signals located within the operons
The predictions are made based on matching of known profiles of the termination signals combined with energy calculations
It is available from the same site as FGENES and BPROM

Discuss Question

Answer: Option B. -> It is a program for searching bacterial ρ-dependent termination signals located within the operons
Answer: (b).It is a program for searching bacterial ρ-dependent termination signals located within the operons

Question 14. Which of the following is correct regarding the method for prokaryotic operon prediction?

It relies on two kinds of information: gene orientation and intergenic distances of a pair of genes of interest and conserved linkage of the genes based on comparative genomic analysis
It relies only on the gene orientation and intergenic distances of a pair of genes of interest
It relies only on the conserved linkage of the genes based on comparative genomic analysis
The prediction cannot be done manually using the rules

Discuss Question

Answer: Option A. -> It relies on two kinds of information: gene orientation and intergenic distances of a pair of genes of interest and conserved linkage of the genes based on comparative genomic analysis
Answer: (a).It relies on two kinds of information: gene orientation and intergenic distances of a pair of genes of interest and conserved linkage of the genes based on comparative genomic analysis

Question 15. Which of the following is incorrect regarding BPROM?

It is a web-based program for prediction of bacterial promoters
It is a web-based program only for prediction of eukarotic promoters
It uses a linear discriminant function
The linear discriminant function is combined with signal and content information

Discuss Question

Answer: Option B. -> It is a web-based program only for prediction of eukarotic promoters
Answer: (b).It is a web-based program only for prediction of eukarotic promoters

Question 16. Which of the following is incorrect regarding Cluster-Buster?

It is an HMM-based web-based program
A query sequence is scanned with a window size of 1 kb for putative regulatory motifs using motif HMMs
It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation
It is designed to find clusters of regulatory binding sites

Discuss Question

Answer: Option C. -> It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation
Answer: (c).It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation

Question 17. McPromoter, a web-based program, uses a neural network to make promoter predictions.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 18. The input for the neural network includes parameters for sequence physical properties, such as ______

DNA bendability
Signals such as the TATA box
Signals such as initiator box
Signals such as CpAA islands

Discuss Question

Answer: Option D. -> Signals such as CpAA islands
Answer: (d).Signals such as CpAA islands

Question 19. Which of the following is incorrect regarding First EF?

It is a program that predicts promoters for bacterial DNA
It is a web-based program that predicts promoters for human DNA
It stands for First Exon Finder
It integrates gene prediction with promoter prediction

Discuss Question

Answer: Option A. -> It is a program that predicts promoters for bacterial DNA
Answer: (a).It is a program that predicts promoters for bacterial DNA

Question 20. TSSW is a web program that distinguishes promoter sequences from non-promoter sequences based on a combination of unique content information such as hexamer/trimer frequencies and signal information such the TATA box in the promoter region.