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Total Questions : 82 | Page 7 of 9 pages
Question 61. To increase the specificity of prediction, a unique feature of eukaryotic promoter is employed, which is the presence of CpG islands.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 62. The eukaryotic transcription initiation is less dependent on transcription factors.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 63. Which of the following is incorrect regarding CONPRO?
  1.    It is a web-based program that uses a consensus method
  2.    It is used to identify promoter elements for human DNA
  3.    cDNA does not play a role in prediction
  4.    The program uses the information to search the human genome database for the position of the gene
 Discuss Question
Answer: Option C. -> cDNA does not play a role in prediction
Answer: (c).cDNA does not play a role in prediction
Question 64. In CONPRO, for each program, the highest score prediction is taken as the promoter in the region.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 65. Which of the following is incorrect regarding Phylogenetic Footprinting–Based Method?
  1.    It is possible to obtain promoter sequences for a particular gene through comparative analysis
  2.    The conservation from closely related organisms is both at the sequence level and at the level of organization of the elements
  3.    The conservation from closely related organisms is most at the sequence level
  4.    It has been observed that promoter and regulatory elements from closely related organisms such as human and mouse are highly conserved
 Discuss Question
Answer: Option C. -> The conservation from closely related organisms is most at the sequence level
Answer: (c).The conservation from closely related organisms is most at the sequence level
Question 66. Which of the following is untrue about ConSite?
  1.    It is a web server that finds putative promoter elements
  2.    It includes comparing two orthologous sequences
  3.    The program does not accept pre-computed alignment
  4.    The program accepts pre-computed alignment
 Discuss Question
Answer: Option C. -> The program does not accept pre-computed alignment
Answer: (c).The program does not accept pre-computed alignment
Question 67. A caveat of phylogenetic footprinting is to extract noncoding sequences Upstream of corresponding genes and focus the comparison to this region only, which helps to prevent false positives.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 68. RVISTA uses two orthologous sequences as input and first identifies all putative regulatory motifs based on TRANSFAC matches.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 69. Which of the following is untrue?
  1.    MEME is the EM based program only for protein motif discovery
  2.    AlignACE is a web-based program using the Gibbs sampling algorithm to find common motifs
  3.    AlignACE is optimized for DNA sequence motif extraction
  4.    Melina stands for Motif Elucidator In Nucleotide sequence Assembly
 Discuss Question
Answer: Option A. -> MEME is the EM based program only for protein motif discovery
Answer: (a).MEME is the EM based program only for protein motif discovery
Question 70. Which of the following is untrue about Bayes Aligner?
  1.    Posterior probability values, which are considered estimates of the true alignment, are calculated for each alignment
  2.    The method generates a single best alignment
  3.    It aligns two sequences using a Bayesian algorithm which is a unique sequence alignment method
  4.    It is a web-based footprinting program
 Discuss Question
Answer: Option B. -> The method generates a single best alignment
Answer: (b).The method generates a single best alignment

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