Questions and answers for exam Preparation

MCQs

Total Questions : 82 | Page 3 of 9 pages

Question 21. INCLUSive is a suite of web based tools designed to streamline the process of microarray data collection and sequence motif detection.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 22. Which of the following is untrue about PhyloCon?

It stands for Phylogenetic Consensus
It is used to identify regulatory motifs
It is a UNIX program that combines phylogenetic footprinting with gene expression profiling analysis
No conservation among orthologous genes and conservation among coregulated genes is a disadvantage

Discuss Question

Answer: Option D. -> No conservation among orthologous genes and conservation among coregulated genes is a disadvantage
Answer: (d).No conservation among orthologous genes and conservation among coregulated genes is a disadvantage

Question 23. Which of the following is untrue about GeneMark?

It is a suite of gene prediction programs based on the fifth-order HMMs
The main program is trained on a number of complete microbial genomes
A GeneMark heuristic program can be used to improve accuracy
If the sequence to be predicted is from a non-listed organism, the most closely related organism can be chosen as the basis for computation

Discuss Question

Answer: Option C. -> A GeneMark heuristic program can be used to improve accuracy
Answer: (c).A GeneMark heuristic program can be used to improve accuracy

Question 24. Which of the following is untrue about Glimmer?

It stands for Gene Locator and Interpolated Markov Modeler
It is a UNIX program from TIGR
It does not necessarily use the IMM algorithm
It is used to predict potential coding regions

Discuss Question

Answer: Option C. -> It does not necessarily use the IMM algorithm
Answer: (c).It does not necessarily use the IMM algorithm

Question 25. In bacteria, the majority of genes have a start codon ATG (orAUG in mRNA; because prediction is done at the DNA level, T is used in place of U), which codes for methionine.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 26. RBS finder is a UNIX program that uses the prediction output from Glimmer and searches for the Shine–Delgarno sequences in the vicinity of predicted start sites.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 27. Which of the following is a wrong statement?

Prokaryotes include bacteria and Archaea
Prokaryotes have relatively large genomes
Prokaryotes have relatively small genomes
In Prokaryotes, The gene density in the genomes is high, with more than 90% of a genome sequence containing coding sequence

Discuss Question

Answer: Option B. -> Prokaryotes have relatively large genomes
Answer: (b).Prokaryotes have relatively large genomes

Question 28. Which of the following is untrue about EST2Genome?

It is a web-based program purely based on the sequence alignment approach to define intron–exon boundaries
It compares an EST (or cDNA) sequence with a genomic DNA sequence containing the corresponding gene
The alignment is rarely done using a dynamic programming–based algorithm
Advantage of the approach is the ability to find very small exons and alternatively spliced exons that are very difficult to predict by any ab initio–type algorithms

Discuss Question

Answer: Option C. -> The alignment is rarely done using a dynamic programming–based algorithm
Answer: (c).The alignment is rarely done using a dynamic programming–based algorithm

Question 29. GenomeScan is a web-based server that combines GENSCAN prediction results with BLASTX similarity searches.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 30. Because different prediction programs have different levels of sensitivity and specificity, it makes sense to combine results of multiple programs based on consensus. This idea has prompted development of consensus-based algorithms.