Questions and answers for exam Preparation

MCQs

Total Questions : 179 | Page 15 of 18 pages

Question 141. How will you determine the intracellular fluid volume?

Evans blue
Na⁺
Difference between total body water and ECF volume
Tritiated water

Discuss Question

Answer: Option C. -> Difference between total body water and ECF volume
Answer: (c).Difference between total body water and ECF volume

Question 142. How a patient’s plasma volume can be determined?

Evans blue
Na⁺
D20
Tritiated water

Discuss Question

Answer: Option A. -> Evans blue
Answer: (a).Evans blue

Question 143. What will be the apparent volume of distribution of warfarin?

The apparent volume of distribution is less than the true volume of distribution
The apparent volume of distribution is more than the true volume of distribution
The apparent volume of distribution is equal to the true volume of distribution
Warfarin is not a medicine

Discuss Question

Answer: Option A. -> The apparent volume of distribution is less than the true volume of distribution
Answer: (a).The apparent volume of distribution is less than the true volume of distribution

Question 144. What will bet the apparent volume of distribution of drugs which binds selectively to extravascular tissues?

The apparent volume of distribution is less than the true volume of distribution
The apparent volume of distribution is more than the true volume of distribution
The apparent volume of distribution is equal to the true volume of distribution
The apparent volume of distribution is equal to the volume of extravascular tissues

Discuss Question

Answer: Option B. -> The apparent volume of distribution is more than the true volume of distribution
Answer: (b).The apparent volume of distribution is more than the true volume of distribution

Question 145. Which kind of drugs are absorbed through endocytosis?

Molecular weight ranging 100-400Dalton
Water-soluble drugs
Macromolecular drugs or drugs as oily droplets
Polar drugs

Discuss Question

Answer: Option C. -> Macromolecular drugs or drugs as oily droplets
Answer: (c).Macromolecular drugs or drugs as oily droplets

Question 146. Which drugs are absorbed through pore transport?

High lipophilicity
Water-soluble drugs of molecular weight less than 100 Dalton
Oily droplets
Affinity for carriers

Discuss Question

Answer: Option B. -> Water-soluble drugs of molecular weight less than 100 Dalton
Answer: (b).Water-soluble drugs of molecular weight less than 100 Dalton

Question 147. What influences the permeation of drugs in an Ionic or Electrochemical diffusion?

Charge on the membrane
Charge on the particle
Concentration gradient
Equilibration of charge

Discuss Question

Answer: Option A. -> Charge on the membrane
Answer: (a).Charge on the membrane

Question 148. Which types of drugs get absorbed by ion-pair transport?

High lipophilicity
Oily droplets
Affinity for carriers
Drugs that ionize at all pH conditions

Discuss Question

Answer: Option D. -> Drugs that ionize at all pH conditions
Answer: (d).Drugs that ionize at all pH conditions

Question 149. Which of these absorption methods involves engulfing of the extracellular drug?

Endocytosis
Passive diffusion
Facilitated diffusion
Ion-Pair transport

Discuss Question

Answer: Option A. -> Endocytosis
Answer: (a).Endocytosis

Question 150. In the case of hydrophobic drugs, micronization results in a decrease in effective surface area and thus fall is dissolution rate. Which of the below sentences cannot be a reason for the given statement?

The hydrophobic surface of the drugs adsorbs onto their surface which inhibits their wettability
The particles reaggregate to form larger particles due to their high surface free energy
Extreme reduction in the particle size imparts surface charges that may prevent wetting
Extreme reduction in the size brings the hydrophobic amino acids to the surface

Discuss Question

Answer: Option D. -> Extreme reduction in the size brings the hydrophobic amino acids to the surface
Answer: (d).Extreme reduction in the size brings the hydrophobic amino acids to the surface