In the case of hydrophobic drugs, micronization results in a decrease in effective surface area and thus fall is dissolution rate. Which of the below sentences cannot be a reason for the given statement? Options: A . &nbspThe hydrophobic surface of the drugs adsorbs onto their surface which inhibits their wettability B . &nbspThe particles reaggregate to form larger particles due to their high surface free energy C . &nbspExtreme reduction in the particle size imparts surface charges that may prevent wetting D . &nbspExtreme reduction in the size brings the hydrophobic amino acids to the surface

In the case of hydrophobic drugs, micronization results in a decrease in effecti

Question

In the case of hydrophobic drugs, micronization results in a decrease in effective surface area and thus fall is dissolution rate. Which of the below sentences cannot be a reason for the given statement?

Options:

A . The hydrophobic surface of the drugs adsorbs onto their surface which inhibits their wettability

B . The particles reaggregate to form larger particles due to their high surface free energy

C . Extreme reduction in the particle size imparts surface charges that may prevent wetting

D . Extreme reduction in the size brings the hydrophobic amino acids to the surface

Answer: Option D
Answer: (d).Extreme reduction in the size brings the hydrophobic amino acids to the surface

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