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MCQs

Total Questions : 179 | Page 18 of 18 pages
Question 171. Which sentence will define the Dissolution rate?
  1.    Amount of solid substrate that goes into solution under constant time
  2.    Amount of solid substrate that goes into solution under constant time under standard temperature
  3.    Amount of solid substrate that goes into solution under constant time under standard temperature, pH, and pressure
  4.    Amount of solid substrate that goes into solution under constant time under standard temperature, pH, solvent composition and constant surface area
 Discuss Question
Answer: Option D. -> Amount of solid substrate that goes into solution under constant time under standard temperature, pH, solvent composition and constant surface area
Answer: (d).Amount of solid substrate that goes into solution under constant time under standard temperature, pH, solvent composition and constant surface area
Question 172. Which one of the following is a critical rate-limiting step of drug absorption?
  1.    Rate of drug disintegration
  2.    Size of the drug
  3.    Size of the porous particle
  4.    Rate of dissolution
 Discuss Question
Answer: Option D. -> Rate of dissolution
Answer: (d).Rate of dissolution
Question 173. What should be the ideal solubility rate of an orally administered drug in the pH range of 2 to 8?
  1.    3-4mg/ml
  2.    4-6 mg/ml
  3.    7-8 mg/ml
  4.    1-2 mg/ml
 Discuss Question
Answer: Option D. -> 1-2 mg/ml
Answer: (d).1-2 mg/ml
Question 174. Which one of these is not a theory of Drug dissolution?
  1.    Diffusion layer model
  2.    Fick’s law of diffusion
  3.    Penetration or surface renewal theory
  4.    Interfacial barrier model
 Discuss Question
Answer: Option B. -> Fick’s law of diffusion
Answer: (b).Fick’s law of diffusion
Question 175. Which theory takes into account that a thin film is created by the solution of the solid at the solid-liquid interface?
  1.    Interfacial barrier model
  2.    Diffusion layer model
  3.    Penetration or surface renewal theory
  4.    Danckwert’s model
 Discuss Question
Answer: Option B. -> Diffusion layer model
Answer: (b).Diffusion layer model
Question 176. In the equation G=Ki (Cs-Cb), what does G stands for______________
  1.    Dissolution rate per unit area
  2.    Effective interfacial transport constant
  3.    Concentration of the solute
  4.    Concentration of the impurity
 Discuss Question
Answer: Option A. -> Dissolution rate per unit area
Answer: (a).Dissolution rate per unit area
Question 177. In the equation, Wo1/3-W1/3=Kt, K stands for ____________
  1.    The original mass of the drug
  2.    Mass of the drug remaining after time t
  3.    Dissolution constant
  4.    Concentration of solute
 Discuss Question
Answer: Option C. -> Dissolution constant
Answer: (c).Dissolution constant
Question 178. What does the interfacial barrier model states?
  1.    An intermediate concentration exists at the interface
  2.    Turbulence in the dissolution medium exists at the solid/liquid interface
  3.    Formation a thin film or layer at the solid-liquid interface
  4.    Solutes passes easily through the interfaces
 Discuss Question
Answer: Option A. -> An intermediate concentration exists at the interface
Answer: (a).An intermediate concentration exists at the interface
Question 179. Which model does not approve the existence of the stagnant layer in the solid-liquid interface?
  1.    Interfacial barrier model
  2.    Diffusion layer model
  3.    Penetration or surface renewal theory
  4.    Danckwert’s model
 Discuss Question
Answer: Option D. -> Danckwert’s model
Answer: (d).Danckwert’s model

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