Questions and answers for exam Preparation

MCQs

Total Questions : 179 | Page 12 of 18 pages

Question 111. What will be the best definition for “carrier”?

Nonpolar drugs can be transported through carrier-mediated transport
Carrier binds reversibly and no covalently with the molecules
It discharges the molecules and gets destroyed itself
The carrier is a protein

Discuss Question

Answer: Option B. -> Carrier binds reversibly and no covalently with the molecules
Answer: (b).Carrier binds reversibly and no covalently with the molecules

Question 112. What is the driving force of Pore Transport?

Hydrostatic pressure
Concertation Gradient
Electrochemical gradient
Charge equilibration

Discuss Question

Answer: Option A. -> Hydrostatic pressure
Answer: (a).Hydrostatic pressure

Question 113. Which kind of molecules cannot pass through a pore transport?

Low Molecular weight molecules
Water-soluble drugs
Molecules up to 400 Dalton
Molecules greater than 400 Dalton

Discuss Question

Answer: Option D. -> Molecules greater than 400 Dalton
Answer: (d).Molecules greater than 400 Dalton

Question 114. What is the major difference between Facilitated diffusion and Passive diffusion?

Carrier-mediated transport
Downhill transport
Energy is used
Inhibition by metabolic poisons

Discuss Question

Answer: Option A. -> Carrier-mediated transport
Answer: (a).Carrier-mediated transport

Question 115. What is the name of the specialized cells that support the blood-brain barrier tissue?

Astrocytes
Dendrites
Fat cells
Endothelial cells

Discuss Question

Answer: Option A. -> Astrocytes
Answer: (a).Astrocytes

Question 116. Which drugs can easily pass the Placental barrier?

Drugs having a molecular weight less than 1000 Dalton
Moderate to high lipid solubility
Drugs having a molecular weight less than 1000 Dalton and moderate to high lipid solubility, analgesics, and antibiotics
Analgesics, antibiotics, etc

Discuss Question

Answer: Option C. -> Drugs having a molecular weight less than 1000 Dalton and moderate to high lipid solubility, analgesics, and antibiotics
Answer: (c).Drugs having a molecular weight less than 1000 Dalton and moderate to high lipid solubility, analgesics, and antibiotics

Question 117. Why dopamine cannot be administered for the disease Parkinsonism?

Don’t have a medicine
It is not the medicine
Cannot cross the blood-brain barrier
Forms aggregate and thus cannot cross the BBB

Discuss Question

Answer: Option C. -> Cannot cross the blood-brain barrier
Answer: (c).Cannot cross the blood-brain barrier

Question 118. What is the function of the blood-testis barrier?

Restricts the passage of drug to the testis
Restricts the passage of drug to sperms
Restricts the passage of drugs to spermatocytes
Restricts the passage of drugs to spermatocytes and spermatids

Discuss Question

Answer: Option D. -> Restricts the passage of drugs to spermatocytes and spermatids
Answer: (d).Restricts the passage of drugs to spermatocytes and spermatids

Question 119. Which one of these is not an approach to make the drug cross the blood-brain barrier?

Using permeation enhancers
Osmotic disruption of the blood-brain barrier
Use of highly lipophilic drug only
Use of drug carriers to cross the BBB

Discuss Question

Answer: Option C. -> Use of highly lipophilic drug only
Answer: (c).Use of highly lipophilic drug only

Question 120. What is the perfusion rate?

The total volume of blood
The volume of blood that flows through the heart per unit time
The volume of blood that flows per unit time per unit volume of tissue
The volume of tissue that flows per unit time per unit area of a blood vessel

Discuss Question

Answer: Option C. -> The volume of blood that flows per unit time per unit volume of tissue
Answer: (c).The volume of blood that flows per unit time per unit volume of tissue