Questions and answers for exam Preparation

MCQs

Total Questions : 165 | Page 13 of 17 pages

Question 121. _______ of the Drosophila sequence is composed of TEs and _____ is heterochromatic regions that do not include genes.

one-fourth, one-third
one-fifth, one-fourth
one-sixth, one-eighth
one-sixth, one-third

Discuss Question

Answer: Option D. -> one-sixth, one-third
Answer: (d).one-sixth, one-third

Question 122. The ________ are _______ by genetic structure to retroviruses.

STR retrotransposons, related
LTR retrotransposons, related
STR transposons, related
LTR retrotransposons, not related

Discuss Question

Answer: Option B. -> LTR retrotransposons, related
Answer: (b).LTR retrotransposons, related

Question 123. Which of the given statement is incorrect?

As in an all-by-all protein comparison within a proteome, a matrix of alignment scores with E values is made, and the most closely related sequences in the two organisms are identified
To perform a between-proteome analysis, proteome databases are made for the known and predicted genes of two or more genomes
Each protein of one proteome is selected in turn as a query of the proteome of another organism or the combined proteome of a group of organisms
Each protein of one proteome is selected in turn as a query of the proteome of another single organism only

Discuss Question

Answer: Option D. -> Each protein of one proteome is selected in turn as a query of the proteome of another single organism only
Answer: (d).Each protein of one proteome is selected in turn as a query of the proteome of another single organism only

Question 124. The higher the E value, the more significant the alignment between a pair of matching sequences.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 125. Yeast is about ______ compact than E. coli.

fivefold, less
threefold, more
twofold, less
twofold, more

Discuss Question

Answer: Option C. -> twofold, less
Answer: (c).twofold, less

Question 126. Which of the given statement is incorrect about proteome analyses?

For BLAST, setting an effective database size appropriate for each search and program is important
Due to the large number of comparisons that must be made in these types of analyses and due to the volume of program output, the procedure must be automated on a local machine using Perl scripts or a similar method and a database system
BLAST is used for obtaining a correct statistical evaluation of alignment scores
BLAST does not give statistical evaluation of alignment scores

Discuss Question

Answer: Option D. -> BLAST does not give statistical evaluation of alignment scores
Answer: (d).BLAST does not give statistical evaluation of alignment scores

Question 127. Evolutionary modeling can include various types of analyses. Which is mostly not one of them?

The prediction of chromosomal rearrangements
Eu/Hetero-chromatin structures
Duplications at gene, chromosomal and full genome level
Duplications at the protein domain level

Discuss Question

Answer: Option B. -> Eu/Hetero-chromatin structures
Answer: (b).Eu/Hetero-chromatin structures

Question 128. Which of the given statement is incorrect about Clusters of functionally related genes?

In microbial genomes, genes specifying a metabolic pathway may be contiguous on the genome where they are coregulated transcriptionally in an operon by a common promoter
In related organisms, gene order on the chromosome is least likely to be conserved
As the relationship between the organisms decreases, local groups of genes remain clustered together, but chromosomal rearrangements move the clusters to other locations
The function of a particular gene can sometimes be predicted, given the known function of a neighboring, closely linked gene

Discuss Question

Answer: Option B. -> In related organisms, gene order on the chromosome is least likely to be conserved
Answer: (b).In related organisms, gene order on the chromosome is least likely to be conserved

Question 129. An all-against-all analysis requires first making a database of the proteome. This database is then sequentially searched by each individual protein sequence of the proteome using a rapid database similarity search tool such as _______

XPBLAST
WU-BLAST
BLAST
FASTA

Discuss Question

Answer: Option A. -> XPBLAST
Answer: (a).XPBLAST

Question 130. Which of the given statement is incorrect about Orthologs?

In comparing two proteomes, a common standard is to require that for each pair of orthologs, the first of the pair is the best hit when the second is used to query the proteome of the first
To identify orthologs, each protein in the proteome of an organism is used as a query in a similarity search of a database comprising the proteomes of only one different organism
The best hit in each proteome is likely to be with an ortholog of the query gene
Orthologs are genes that are so highly conserved by sequence in different genomes that the proteins they encode are strongly predicted to have the same structure and function and to have arisen from a common ancestor through speciation

Discuss Question

Answer: Option B. -> To identify orthologs, each protein in the proteome of an organism is used as a query in a similarity search of a database comprising the proteomes of only one different organism
Answer: (b).To identify orthologs, each protein in the proteome of an organism is used as a query in a similarity search of a database comprising the proteomes of only one different organism