Questions and answers for exam Preparation

MCQs

Total Questions : 100 | Page 9 of 10 pages

Question 81. Which of the following is untrue about Ab initio prediction?

The limited knowledge of protein folding forms the basis of ab initio prediction
The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone without the aid of known protein structures
The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone with some aid of known protein structures
The perceived advantage of this method is that predictions are not restricted by known folds and that novel protein folds can be identified

Discuss Question

Answer: Option C. -> The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone with some aid of known protein structures
Answer: (c).The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone with some aid of known protein structures

Question 82. Searching for a fold with the absolute minimum energy may not be valid in reality.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 83. The prediction programs are thus designed using the energy minimization principle.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 84. In Rosetta, The segments with assigned _______ structures are subsequently assembled into a ______ dimensional configuration.

primary, three
secondary, three
secondary, two
primary, three

Discuss Question

Answer: Option B. -> secondary, three
Answer: (b).secondary, three

Question 85. Rosetta is a web server that predicts protein three-dimensional conformations using the ab initio method.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 86. Globular proteins are usually insoluble.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 87. Which of the following is not correct about the NMR?

It stands for Nuclear Magnetic Resonance
NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field
NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field
Protein samples are labeled with radioisotopes such as 13C and 15N

Discuss Question

Answer: Option B. -> NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field
Answer: (b).NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field

Question 88. Which of the following is not correct about the Integral Membrane Proteins?

Membrane proteins exist in lipid bilayers of cell membranes
The exterior of the proteins spanning the membrane must be very hydrophobic to be stable
The exterior of the proteins spanning the membrane must be very hydrophilic to be stable
Most typical transmembrane segments are α-helices

Discuss Question

Answer: Option C. -> The exterior of the proteins spanning the membrane must be very hydrophilic to be stable
Answer: (c).The exterior of the proteins spanning the membrane must be very hydrophilic to be stable

Question 89. Which of the following is not correct about the X-ray Crystallography?

In x-ray protein crystallography, proteins need to be grown into large crystals in which their positions are fixed in a repeated, ordered fashion
The protein crystals are illuminated with an intense x-ray beam
The x-rays are deflected by the electron clouds surrounding the atoms in the crystal producing a regular pattern of diffraction
The protein crystals are illuminated with an intense infrared beam

Discuss Question

Answer: Option D. -> The protein crystals are illuminated with an intense infrared beam
Answer: (d).The protein crystals are illuminated with an intense infrared beam

Question 90. One can search a structure in PDB using the four-letter code or keywords related to its annotation.