Questions and answers for exam Preparation

MCQs

Total Questions : 100 | Page 8 of 10 pages

Question 71. Members within the ____ fold ______ have evolutionary relationships.

same, always
same, do not always
one, always
different, do not

Discuss Question

Answer: Option B. -> same, do not always
Answer: (b).same, do not always

Question 72. Which of the following is untrue about SCOP and CATH?

The definition for class in CATH is quite dissimilar to that in SCOP
The definition for class in CATH is based on secondary structure content
Architecture is a unique level in CATH, intermediate between fold and class
The definition for class in CATH is similar to that in SCOP

Discuss Question

Answer: Option D. -> The definition for class in CATH is similar to that in SCOP
Answer: (d).The definition for class in CATH is similar to that in SCOP

Question 73. In CATH, Structural domain separation is carried by ___________

manual comparison only
computer programs only
human expertise only
a combined effort of a human expert and computer programs

Discuss Question

Answer: Option D. -> a combined effort of a human expert and computer programs
Answer: (d).a combined effort of a human expert and computer programs

Question 74. SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins.

entirely
almost entirely
not
partially

Discuss Question

Answer: Option B. -> almost entirely
Answer: (b).almost entirely

Question 75. CATH is a combination of manual curation and automated procedure, which makes the process less subjective.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 76. Which of the following is untrue regarding Prediction with Neural Networks?

When multiple sequence alignments and neural networks are combined, the result is further improved accuracy
A neural network is trained by a single sequence
A neural network is trained by a sequence profile derived from the multiple sequence alignment
When the sufficiently trained network processes an unknown sequence, it applies the rules learned in training to recognize particular structural patterns

Discuss Question

Answer: Option B. -> A neural network is trained by a single sequence
Answer: (b).A neural network is trained by a single sequence

Question 77. Which of the following is untrue regarding PHD?

It stands for Profile network from Heidelberg
It is a web-based program that combines neural network only
It first performs a BLASTP of the query sequence against a non redundant protein sequence database
In initial steps it finds a set of homologous sequences, which are aligned with the MAXHOM program (a weighted dynamic programming algorithm performing global alignment)

Discuss Question

Answer: Option B. -> It is a web-based program that combines neural network only
Answer: (b).It is a web-based program that combines neural network only

Question 78. Which of the following is untrue regarding the transmembrane proteins?

Constitute up to 30% of all cellular proteins
They are responsible for performing a wide variety of important functions in a cell, such as signal transduction, cross-membrane transport, and energy conversion
The membrane proteins are also of tremendous biomedical importance
They are not drug targets or receptors

Discuss Question

Answer: Option D. -> They are not drug targets or receptors
Answer: (d).They are not drug targets or receptors

Question 79. The structures of this group of proteins, however, are comparatively a lot difficult to resolve either by x-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 80. Which of the following is untrue regarding Prediction of Helical Membrane Proteins?

For membrane proteins consisting of transmembrane α–helices, these transmembrane helices are predominantly hydrophobic with a specific distribution of positively charged residues
The α-helices generally run perpendicular to the membrane plane
The α-helices generally run parallel to the membrane plane
The α-helices have an average length between seventeen and twenty-five residues

Discuss Question

Answer: Option C. -> The α-helices generally run parallel to the membrane plane
Answer: (c).The α-helices generally run parallel to the membrane plane