Questions and answers for exam Preparation

MCQs

Total Questions : 41 | Page 4 of 5 pages

Question 31. In the equation X= Vd C, what does X stands for?

Amount of drug in the blood
Amount of drug in plasma
Amount of drug in the tablet
Amount of drug in the body

Discuss Question

Answer: Option D. -> Amount of drug in the body
Answer: (d).Amount of drug in the body

Question 32. Following is the order in decreasing order of drug binding to the extravascular tissue. Which one is the correct order?

Liver > kidney > muscle > lung
Liver > muscle > lung > kidney
Liver > muscle > kidney > lung
Liver > kidney > lung > muscle

Discuss Question

Answer: Option D. -> Liver > kidney > lung > muscle
Answer: (d).Liver > kidney > lung > muscle

Question 33. What is the relation between halogenated hydrocarbon and liver?

Halogenated hydrocarbon is a drug for liver problems
Halogenated hydrocarbon is nutrition for liver
Halogenated hydrocarbon causes hepatotoxicity
Halogenated hydrocarbon forms the bile juices in liver

Discuss Question

Answer: Option C. -> Halogenated hydrocarbon causes hepatotoxicity
Answer: (c).Halogenated hydrocarbon causes hepatotoxicity

Question 34. What reasons make tissue-drug binding important for drug distribution?

Increases the volume of distribution of drugs and results in localization of drug at a specific site
Increases the volume of distribution of drugs
Results in localization of drugs at a tissue specific site
Increases in absorption from the tissue due to concentration increasing

Discuss Question

Answer: Option A. -> Increases the volume of distribution of drugs and results in localization of drug at a specific site
Answer: (a).Increases the volume of distribution of drugs and results in localization of drug at a specific site

Question 35. Which drugs accumulate in liver?

Acidic drugs like imipramine
Basic drugs like imipramine
Halogenated hydrocarbons
Chloroquinine

Discuss Question

Answer: Option B. -> Basic drugs like imipramine
Answer: (b).Basic drugs like imipramine

Question 36. Which metals get accumulated in the kidney?

Mercury, cadmium, lead
Mercury, cadmium, iron
Mercury, lanthanum, lead
Mercury, cadmium, fluoride ions

Discuss Question

Answer: Option A. -> Mercury, cadmium, lead
Answer: (a).Mercury, cadmium, lead

Question 37. Penicillin has short plasma half-life although it can bind to plasma protein rigidly.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 38. What kind of graph is shown in the picture?

Direct plot
Scatchard plot
Double reciprocal plot
Michele’s menten plot

Discuss Question

Answer: Option A. -> Direct plot
Answer: (a).Direct plot

Question 39. Displacement interactions are significant in the case of drugs which are more than 95% bound.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 40. Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.