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MCQs

Total Questions : 41 | Page 3 of 5 pages
Question 21. What is the name of the drug binding site III of HSA?
  1.    Tamoxifen binding site
  2.    Digitoxin binding site
  3.    Diazepam binding site
  4.    Warfarin and azapropazone binding site
 Discuss Question
Answer: Option B. -> Digitoxin binding site
Answer: (b).Digitoxin binding site
Question 22. Which drugs results in distortion of double stranded DNA structure?
  1.    Arsenicals
  2.    Quinacrine
  3.    Halogenated hydrocarbons
  4.    Lipophilic drug
 Discuss Question
Answer: Option B. -> Quinacrine
Answer: (b).Quinacrine
Question 23. Which one of the following factors related to protein-drug binding is not related to drugs?
  1.    Physicochemical characteristics of a drug
  2.    The concentration of the drug in the body
  3.    The affinity of the drug for binding
  4.    Number of binding sites on the binding agent
 Discuss Question
Answer: Option D. -> Number of binding sites on the binding agent
Answer: (d).Number of binding sites on the binding agent
Question 24. Which one of the following factor related to protein-drug binding is not related to drug interactions with the binding site?
  1.    Competition between the drug and the binding site
  2.    Competition between drugs and normal body constituents
  3.    Allosteric changes in a protein molecule
  4.    Inter subject variation
 Discuss Question
Answer: Option D. -> Inter subject variation
Answer: (d).Inter subject variation
Question 25. Which of the following factors for protein drug binding is a drug interaction factor?
  1.    Competition between drugs for the binding site
  2.    Age
  3.    Physicochemical characteristics of a drug
  4.    Physicochemical characteristics of the protein or binding agent
 Discuss Question
Answer: Option A. -> Competition between drugs for the binding site
Answer: (a).Competition between drugs for the binding site
Question 26. Which drugs bind to HSA easily?
  1.    Cationic drug
  2.    Anionic drug
  3.    Lipophilic drug
  4.    Neutral drug
 Discuss Question
Answer: Option B. -> Anionic drug
Answer: (b).Anionic drug
Question 27. Which drug easily bind to AAG?
  1.    Cationic drug
  2.    Anionic drug
  3.    Lipophilic drug
  4.    Neutral drug
 Discuss Question
Answer: Option A. -> Cationic drug
Answer: (a).Cationic drug
Question 28. Which drugs easily bind to adipose tissue?
  1.    Cationic drug
  2.    Anionic drug
  3.    Lipophilic drug
  4.    Neutral drug
 Discuss Question
Answer: Option C. -> Lipophilic drug
Answer: (c).Lipophilic drug
Question 29. Only unbound or free drug is capable of being eliminated.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 30. The extent of drug-protein binding can change with both changes in protein and drug concentration.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True

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