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12th Grade > Biology

MOLECULAR BASIS OF INHERITANCE MCQs

Total Questions : 56 | Page 6 of 6 pages
Question 51. Transformation experiments in bacteria were first performed by
  1.    MacLeod
  2.    Griffith
  3.    Pasteur
  4.    Meselson and Stahl
 Discuss Question
Answer: Option B. -> Griffith
:
B
Transformation experiments in bacteria were first performed by Frederick Griffith in 1928. He performed the experiment to understand the nature of the hereditary material in cells.
Question 52. The Operon regulates the gene expression at what level?
  1.    Inhibiting transcription of mRNA
  2.    Inhibiting enzymes
  3.    Inhibiting passage of mRNA
  4.    Inhibiting substrate-enzyme reaction
 Discuss Question
Answer: Option A. -> Inhibiting transcription of mRNA
:
A
Gene regulation can happen at various stages of protein synthesis. In the operon model, gene regulation happens at the transcriptional level, wherein the transcription of the respective gene and the production of mRNA is stopped by the regulator, as per requirement.
Question 53. Anticodon is made of
  1.    Three adjacent nitrogen bases
  2.    Unpaired triplet bases on mRNA
  3.    Paired triplet of nitrogen bases on tRNA
  4.    Unpaired triplet of nitrogen bases at one end of tRNA
 Discuss Question
Answer: Option D. -> Unpaired triplet of nitrogen bases at one end of tRNA
:
D
Anticodon is the unpaired triplet of N2bases at one end of tRNA. The anticodon is used in identifying the mRNA sequence that will decide the amino acid for the polypeptide.
Question 54. Which of the following is TRUE?
  1.    DNA polymerase reads in 3’-5’ direction, but RNA polymerase reads in 5’-3’ direction
  2.    DNA polymerase reads in 3’-5’ direction and RNA polymerase reads in 3’-5’ direction
  3.    DNA polymerase reads in 5’-3’ direction but RNA polymerase reads in 3’-5’ direction
  4.    DNA polymerase reads in 5’-3’ direction and RNA polymerase reads in 5’-3’ direction
 Discuss Question
Answer: Option B. -> DNA polymerase reads in 3’-5’ direction and RNA polymerase reads in 3’-5’ direction
:
B
All polymerases read in 3’-5’ direction. This means that the templates which they copy from, run in the 3’-5’ direction.
Question 55. Transcription involves
  1.    Synthesis of RNA from DNA
  2.    Joining of amino acids
  3.    Synthesis of RNA by ribosomes
  4.    Synthesis of DNA from RNA
 Discuss Question
Answer: Option A. -> Synthesis of RNA from DNA
:
A
Transcription involves the synthesis of mRNA using DNA as the template. DNA molecule unwinds and only one strand is used as the template. This is the first step in the central dogma of molecular biology and it takes places in the nucleus.
Question 56. Sickle cell anaemia is an example of
  1.    Single base substitution mutation
  2.    Insertion of a single base
  3.    Non-frameshift mutation
  4.    Deletion of a single base
 Discuss Question
Answer: Option A. -> Single base substitution mutation
:
A
Sickle cell anaemia is caused by the substitution of a single nucleotide in the gene sequence, which eventually leads to the replacement of the amino acid glutamic acid with valine, affecting the final protein formed.

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