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12th Grade > Biology

MOLECULAR BASIS OF INHERITANCE MCQs

Total Questions : 56 | Page 4 of 6 pages
Question 31. Deletion mutation can also cause frameshift mutation.
  1.    True
  2.    False
  3.    DNA has Uracil and RNA has Thymine
  4.    None of the above
 Discuss Question
Answer: Option A. -> True
:
A
Deletion mutation is the one in which one or a few bases get deleted from the gene. If the number of deleted bases happens to be 1, 2 or any non-multiple of 3, it can cause a frameshift mutation.
Question 32. Nonsense codon takes part in
  1.    Terminating the process of protein synthesis
  2.    Formation of unspecified amino acids
  3.    Conversion of sense DNA into nonsense one
  4.    Releasing tRNA from polypeptide chain
 Discuss Question
Answer: Option A. -> Terminating the process of protein synthesis
:
A
Nonsense codons are those that terminate the translation process since there are no corresponding tRNA molecules with anticodons for them. They are also called stop codons and there are three of them: UAA, UAG, UGA.
Question 33. The main goal of human genome project was 
  1.    find the total number of chromosomes in the nucleus 
  2.    sequence all the DNA base pairs in the genome 
  3.    find number of nitrogenous base pairs in the genome
  4.    find the number of genes of one chromosome in the genome 
 Discuss Question
Answer: Option B. -> sequence all the DNA base pairs in the genome 
:
B
Genomeis an organism's complete set of DNA, including all of its genes. The genomecontains all of the information needed to build and maintain that organism. Each organism has different numbers of genes according to their physiological needs.
The maingoalsof theHuman Genome Projectwere to provide a complete and accurate sequence of the 3 billion DNA base pairs that make up thehuman genomeand to find all of the estimated 20,000 to 25,000humangenes.
Question 34. Match the names of the scientists listed in Column-I with their respective discoveries in Column-II.
ColumnIColumnIIp.Watson and Cricki. Confirmed that DNA is the transforming principleq.Avery,MacLeod and McCartyii.DNA double helical modelr.Hershey and Chaseiii.First identified DNA as the transforming principles.Griffithiv.Existence of a transforming principle
 
 
  1.    p - ii, q - iii, r - i, s - iv
  2.    p - iii, q - i, r - iv, s - ii
  3.    p - ii, q - iv, r - i, s - iii
  4.    p - iv, q - i, r - ii, s - iii
 Discuss Question
Answer: Option A. -> p - ii, q - iii, r - i, s - iv
:
A
Watson and Crick are known for the double helical model of DNA that they constructed. Griffith’s transformation experiments revealed that a “transforming principle” from heat-killed S strain of pneumococcal bacteria could transform the R strain into the live S strain. Avery, MacLeod and McCarty figured out that DNA isthe “transforming principle”. Hershey and Chase, through a cleverly developed experiment, re-confirmed that DNA, and not protein, is the genetic material in most organisms.
Question 35. DNA polymerase adds nucleotides to the free ___ end of RNA primers.
 Discuss Question

:
DNA polymerase can add nucleotides only to the free 3’ end of RNA primers. Thus it works exclusively in the 5’3’ direction, which basically means that DNA replication follows the 5’3’ direction.
Question 36. Which of the following has RNA as its genetic material?
  1.    E. coli
  2.    Tobacco Mosaic Virus 
  3.    Agrobacterium
  4.    Amoeba
 Discuss Question
Answer: Option B. -> Tobacco Mosaic Virus 
:
B
Tobacco mosaic virusis a rodlike virus. TMV capsids are composed of identical protein subunits, which assemble around the viral ssRNA to form a helical structure, with a hollow central cavity.
Question 37. How does the pyrimidine composition change between DNA and RNA?
  1.    DNA is mostly made up of pyrimidines
  2.    DNA has Thymine and RNA has Uracil
  3.    DNA has Uracil and RNA has Thymine
  4.    None of the above
 Discuss Question
Answer: Option B. -> DNA has Thymine and RNA has Uracil
:
B
There are three types of pyrimidines - Cytosine, Thymine and Uracil. DNA has Cytosine and Thymine, while RNA has Cytosine and Uracil.
Question 38. Nucleic acids are polymers of
  1.    Amino acids
  2.    Nucleotides
  3.    Nitrogenous bases
  4.    Nucleosides
 Discuss Question
Answer: Option B. -> Nucleotides
:
B
Nucleic acids are biological macromolecules which are polymers of repeating monomeric units called nucleotides. A single nucleotide includes a nitrogenous base, a sugar molecule, and a phosphate group. A nitrogenous base with a sugar molecule alone makes up a nucleoside.
Question 39. Which of these is NOT a part of the transcription unit?
  1.    Terminator
  2.    Promoter
  3.    Introns
  4.    Exons
 Discuss Question
Answer: Option B. -> Promoter
:
B
Introns and exons are formed in a process called post-transcriptional modification. This takes place after transcription is carried out. Therefore before transcription, they are found combined together and are collectively known as the RNA coding region or the Gene. The terminator sequence is also required for the RNA polymerase to stop copying things down and hence included in the transcription unit, although it does not form a part of the structural or core Gene. The promoter however, is present on the strand just to help RNA polymerase recognise the transcription unit. In some cases still, RNA polymerase will be bound to the promoter and another part of the transcription unit, like a repressor, will be blocking its activity, as is the case in the Lac Operon.
Question 40. A bacteriophage is a type of
  1.    Bacteria that attack viruses
  2.    Fungus that attacks bacteria
  3.    Protozoan
  4.    Virus that infects bacteria
 Discuss Question
Answer: Option D. -> Virus that infects bacteria
:
D
A bacteriophage is a type of virus that infects bacteria. It acts as a medium of gene transfer among bacteria by the process called transduction (phage-mediated gene transfer).

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