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12th Grade > Biology

MOLECULAR BASIS OF INHERITANCE MCQs

Total Questions : 56 | Page 3 of 6 pages
Question 21. Which of the following scientists provided indirect evidence to support the fact that DNA is the genetic material in most organisms?
  1.    Gregor Mendel, Walter Sutton, T.H. Morgan
  2.    Alfred Hershey and Martha Chase
  3.    James Watson and Francis Crick
  4.    Rosalind Franklin and Maurice Wilkins
 Discuss Question
Answer: Option A. -> Gregor Mendel, Walter Sutton, T.H. Morgan
:
A
The experiments by Mendel, Sutton and Morgan did not directly involve DNA. However, they did play a major role in paving way for research in genetics in the right direction. The other scientists (mentioned in the options) worked directly with DNA in their respective experiments.
Question 22. Why were laws passed to control the usage of knowledge of human genome?
  1.    Humans are always prone to exploit any new knowledge to their benefit and often at the cost of the cost of another individual’s harm.
  2.    The genome of an individual is considered to be personal property and needs to be protected by law.
  3.    The knowledge of an individual’s genome could be used to inflict harm.
  4.    All the above
 Discuss Question
Answer: Option D. -> All the above
:
D
Humans have had a dubious history of using new knowledge for a negative purpose. Moreover, the human genome is a very personal information. It is almost like knowing another person’s name, bank account number, ATM PIN cards and passwords to e-mail accounts. It is very important to protect the knowledge of human genome with laws that prevent unlawful usage.
Question 23. Identify the molecule in the following image:
Identify The Molecule In The Following Image:
  1.    Ribonucleic acid
  2.    Deoxyribonucleic acid
  3.    Ribonucleotide
  4.    Deoxyribonucleotide
 Discuss Question
Answer: Option A. -> Ribonucleic acid
:
A
The given structure shows a few nucleotides bonded together to form a long chain, which indicates that the molecule is a nucleic acid and not an individual nucleotide. The sugar molecule in the given structure is ribose, and hence, the molecule has to be ribonucleic acid. Moreover, there is a molecule of uracil shown as part of this polymer, which too, gives a hint that it is RNA and not DNA.
Question 24. State whether true or false:
The anticodon loop of a specific tRNA molecule contains a set of three nucleotide bases which are complementary to the codon of the respective amino acid it carries on the AA binding site.
  1.    True
  2.    False
  3.    Ribonucleotide
  4.    Deoxyribonucleotide
 Discuss Question
Answer: Option A. -> True
:
A
Codon is a set of three nucleotide bases on the mRNA strand, and codes for a specific amino acid. Each tRNA molecule carries a specific amino acid at its amino acid (AA) binding site or amino acid acceptor arm. The loop opposite to it (as seen in the clover leaf structure) is called the anticodon loop, which contains a set of three nucleotide bases complementary to the codon of the respective amino acid.
Question 25. Matching DNA sequences to identify a criminal is known as ________.
  1.    DNA fingerprinting 
  2.    DNA amplification 
  3.    Gene mapping 
  4.    DNA resolution
 Discuss Question
Answer: Option A. -> DNA fingerprinting 
:
A
DNA fingerprinting is a technique used in forensic investigations to identify criminals. The DNA of the suspects and the DNA sample collected at the crime scene are compared to check if the criminal is one among those suspects.
Question 26. The TATA box is a part of the  _________ region.
  1.    Terminator
  2.    Promoter
  3.    Repressor
  4.    Transcription unit
 Discuss Question
Answer: Option B. -> Promoter
:
B
The first step of transcription is called initiation, during which the enzyme RNA polymerase binds on to the promoter region. Many eukaryotic genes have a conserved promoter sequence to begin with, called the TATA box, located 25 to 35 base pairs upstream of the transcription unit. This region always has the sequence TATAAA on one DNA strand, and ATATTT on the complementary strand. RNA polymerase specifically identifies this region on the DNA molecule to initiate transcription.
Question 27. Segments of mRNA removed during splicing are ________.
  1.    Introns
  2.    Exons
  3.    Promoter regions
  4.    Integrator regions
 Discuss Question
Answer: Option A. -> Introns
:
A
In eukaryotes, the DNA includes introns and exons. Introns are the non-coding regions that are removed from the mRNA during splicing. Only the exons, which actually code for genes, are retained.
Question 28. The specific nucleotide sequences repeated multiple times in the genome of an individual are known as
  1.    STRs
  2.    Introns
  3.    Exons
  4.    Promoter
 Discuss Question
Answer: Option A. -> STRs
:
A
STRs or Short Tandem Repeats are certain specific nucleotide sequences in the human genome, which are repeated multiple times. The number of these repeats is unique for each individual. STRs do not code for any protein, and thus, are found in the noncoding parts of DNA. Identification of the number of these STRs is basically the key step in DNA fingerprinting.
Question 29. Correct sequence of code transfer during polypeptide formation is
  1.    DNA, mRNA, tRNA and amino acids
  2.    DNA, tRNA, rRNA and mRNA 
  3.    mRNA, tRNA, DNA and amino acids
  4.    rRNA, DNA, mRNA and tRNA
 Discuss Question
Answer: Option A. -> DNA, mRNA, tRNA and amino acids
:
A
The correct sequence of code transfer during polypeptide formation is DNA mRNA tRNA amino acids. This is known as the central dogma of molecular biology.The information in DNA is carried by messenger RNA to the site where proteins can be made, which is the ribosome. According to the information in the mRNA, tRNA brings in the correct amino acid in the respective sequence, eventually forming the polypeptide.
Question 30. Match the following regarding transcription:
 
p. Initiationi. Ribonucleotides arepolymerised according to the codeq. Elongationii. RNA polymerase binds to TATA boxr. Terminationiii. mRNA is bound by protective moleculess. Cappingiv. RNA polymerase detaches from DNA
  1.    p-i, q-ii, r-iii, s-iv
  2.    p-ii, q-iii, r-iv, s-i
  3.    p-ii, q-i, r-iv, s-iii
  4.    p-iv, q-iii, r-ii, s-i
 Discuss Question
Answer: Option C. -> p-ii, q-i, r-iv, s-iii
:
C
Transcription takes place in three major steps- initiation, elongation and termination. Initiation involves binding of RNA polymerase to the TATA box. This is followed by addition or polymerisation of ribonucleotides according to the template. The last step is termination, during which RNA polymerase detaches from the parental DNA in order to end the transcription process. The newly formed mRNA then undergoes processing, which involves capping and tailing by protective molecules.

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