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MCQs

Total Questions : 101 | Page 4 of 11 pages
Question 31. What is the main damaging effect of UV radiation on DNA?
  1.    Single strand break
  2.    Dehydration
  3.    Formation of thymine dimers
  4.    Depurination
 Discuss Question
Answer: Option C. -> Formation of thymine dimers
Question 32. E.coli DNA polymerases II and III lack
  1.    5' → 3' endonuclease activity
  2.    partially 5' → 3' endonuclease activity
  3.    5' → 3' exonuclease activity
  4.    partially 5' → 3' exonuclease activity
 Discuss Question
Answer: Option C. -> 5' → 3' exonuclease activity
Question 33. DNA helicase is used to
  1.    break a phosphodiester bond in DNA strand
  2.    interact the double helix closely
  3.    None of these
  4.    unwind the double helix
 Discuss Question
Answer: Option D. -> unwind the double helix
Question 34. The higher order structure of DNA shows symmetry, whereas the higher order structures of most proteins do not. Why isn't protein shape more regular like DNA?
  1.    The many different amino acid R groups on proteins confer many different shapes.
  2.    DNA has one main function in cells whereas proteins have many.
  3.    Some S amino acids cause proteins to bend; others cause protein to flatten.
  4.    All of these
 Discuss Question
Answer: Option D. -> All of these
Question 35. Klenow fragment without free nucleotides exhibits
  1.    no activity
  2.    nickase activity
  3.    endonuclease activity
  4.    exonuclease activity
 Discuss Question
Answer: Option D. -> exonuclease activity
Question 36. Each replication bubbles consists of
  1.    3 replication forks
  2.    2 replication forks
  3.    1 replication forks
  4.    4 replication forks
 Discuss Question
Answer: Option B. -> 2 replication forks
Question 37. Which histone(s) are associated with the linker DNA of a nucleosome?
  1.    Histone H1
  2.    Histone H4
  3.    Histones H2A and H2B
  4.    Histone H3
 Discuss Question
Answer: Option A. -> Histone H1
Question 38. DNA can be sequenced by the
  1.    chain termination procedure
  2.    physical method
  3.    both (a) and (b)
  4.    chemical method
 Discuss Question
Answer: Option C. -> both (a) and (b)
Question 39. Okazaki fragments occur during
  1.    polymerase reaction
  2.    synthesis
  3.    replication
  4.    transformation
 Discuss Question
Answer: Option C. -> replication
Question 40. In sperm heads, DNA is particularly highly condensed and the histones are replaced with small basic protein called
  1.    pyrimidines
  2.    purines
  3.    protamines
  4.    All of these
 Discuss Question
Answer: Option C. -> protamines

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