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MCQs

Total Questions : 101 | Page 7 of 11 pages
Question 61. Overwinding or overtightening of DNA during replication is caused and removed by
  1.    DNAb, gyrase
  2.    DNAa, gyrase
  3.    DNAb, DNA polymerase
  4.    Single stranded protein, DNAa
 Discuss Question
Answer: Option A. -> DNAb, gyrase
Question 62. The enzyme responsible for breaking the hydrogen bonds, and thus separating the DNA strands during DNA synthesis is
  1.    none of these
  2.    DNA polymerase
  3.    strandase
  4.    helicase
 Discuss Question
Answer: Option D. -> helicase
Question 63. Number of times the two DNA strands are interwined in circular DNA and is known as
  1.    linking number
  2.    helix frequency
  3.    twisting number
  4.    none of these
 Discuss Question
Answer: Option A. -> linking number
Question 64. How does ethidium bromide interact with DNA?
  1.    It binds to phosphate
  2.    It binds to adenine
  3.    It does not interact
  4.    It intercalates between bases
 Discuss Question
Answer: Option D. -> It intercalates between bases
Question 65. Which of the following species lack a 'classical' histone H1?
  1.    Strongylocentrotus purpuratus
  2.    Xenopus laevis
  3.    Arabidopsis thaliana
  4.    Saccharomyces cerevisiae
 Discuss Question
Answer: Option D. -> Saccharomyces cerevisiae
Question 66. The size of a linear DNA fragment in a gel can be estimated by
  1.    comparison with a molecular weight standard such as Hind III digested phage lambda
  2.    fluorescence in UV light
  3.    the time it takes the gel to run
  4.    the sedimentation coefficient
 Discuss Question
Answer: Option A. -> comparison with a molecular weight standard such as Hind III digested phage lambda
Question 67. Which of these drugs bind to DNA and cuts it, producing hydroxyl radicals?
  1.    Erythromycin
  2.    Bleomycin
  3.    Tunicamycin
  4.    All of these
 Discuss Question
Answer: Option B. -> Bleomycin
Question 68. DNA replication results in
  1.    two DNA molecules such that each one contains a strand of the original
  2.    one new molecule of RNA
  3.    one new DNA molecules 1 old molecule
  4.    two completely new DNA molecules
 Discuss Question
Answer: Option A. -> two DNA molecules such that each one contains a strand of the original
Question 69. Which of the following are short nucleotides strands made by DNA polymerase working in the opposite direction of the replication fork?
  1.    Leading strands
  2.    Primers
  3.    Lagging strand
  4.    Okazaki fragments
 Discuss Question
Answer: Option D. -> Okazaki fragments
Question 70. Replication in E. coli is initiated by the generation of short RNA primers using
  1.    reverse transcriptase
  2.    RNA polymerase
  3.    primase
  4.    both (a) and (b)
 Discuss Question
Answer: Option D. -> both (a) and (b)

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