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MCQs

Total Questions : 60 | Page 5 of 6 pages
Question 41. What are soft drugs?
  1.    Drugs given to babies
  2.    Chemical drugs which are already found in the body
  3.    Nutrients which kill the gut harmful microbes
  4.    Anything that is not nutrients and enters the body through different routes
 Discuss Question
Answer: Option B. -> Chemical drugs which are already found in the body
Answer: (b).Chemical drugs which are already found in the body
Question 42. Which of the following is the correct decreasing order of drug metabolism?
  1.    Liver > lungs > kidneys > intestine > placenta > skin > adrenals
  2.    Liver > lungs > kidneys > intestine > adrenals > placenta > skin
  3.    Liver > kidneys > lungs > intestine > placenta > adrenals > skin
  4.    Liver > lungs > intestine > kidneys > placenta > adrenals > skin
 Discuss Question
Answer: Option A. -> Liver > lungs > kidneys > intestine > placenta > skin > adrenals
Answer: (a).Liver > lungs > kidneys > intestine > placenta > skin > adrenals
Question 43. The enzymes are divided into two categories, these are _______ and ____________
  1.    Acidic drug metabolizing and basic drug metabolizing
  2.    Present in the liver and not present in the liver
  3.    Microsomal and non-microsomal
  4.    There is no such division
 Discuss Question
Answer: Option C. -> Microsomal and non-microsomal
Answer: (c).Microsomal and non-microsomal
Question 44. Microsome are selective to ____________
  1.    Water-soluble drugs
  2.    Lipid soluble drugs
  3.    Acidic drugs
  4.    Basic drugs
 Discuss Question
Answer: Option B. -> Lipid soluble drugs
Answer: (b).Lipid soluble drugs
Question 45. Where are non-microsomal enzymes present?
  1.    In the Golgi apparatus
  2.    Inside lysosomes
  3.    In the cytoplasm in soluble form
  4.    In oxysomes
 Discuss Question
Answer: Option C. -> In the cytoplasm in soluble form
Answer: (c).In the cytoplasm in soluble form
Question 46. Which one is the rate-limiting step in the oxidation of xenobiotics?
  1.    Binding of the substrate to Fe³⁺
  2.    Electron transfer from NADPH to the above complex
  3.    The enzyme-substrate complex combines with a molecule of oxygen forming a ternary complex
  4.    Ternary complex gains an electron from the NADPH
 Discuss Question
Answer: Option B. -> Electron transfer from NADPH to the above complex
Answer: (b).Electron transfer from NADPH to the above complex
Question 47. Which one of the following is reactive and a known carcinogenic?
  1.    Cytochrome P-450
  2.    Catechol
  3.    Glutathione
  4.    Arene oxide
 Discuss Question
Answer: Option D. -> Arene oxide
Answer: (d).Arene oxide
Question 48. What is the major end product of oxidation of aromatic carbon atoms?
  1.    Arenols
  2.    Catechol
  3.    Glutathione
  4.    Arene oxide
 Discuss Question
Answer: Option A. -> Arenols
Answer: (a).Arenols
Question 49. Which of the following is not a common N containing functional groups which undergo reduction reactions?
  1.    Nitro compounds
  2.    Azo compounds
  3.    N-oxide compounds
  4.    Nitrite compounds
 Discuss Question
Answer: Option D. -> Nitrite compounds
Answer: (d).Nitrite compounds
Question 50. What provides the atom of oxygen for the making of water?
  1.    From the cytochrome 450
  2.    From the environment
  3.    From the activated oxygen P-450 substrate complex
  4.    From cytochrome reductase
 Discuss Question
Answer: Option C. -> From the activated oxygen P-450 substrate complex
Answer: (c).From the activated oxygen P-450 substrate complex

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