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MCQs

Total Questions : 60 | Page 3 of 6 pages
Question 21. Which enzyme is important in the Phase II reactions?
  1.    Esterase
  2.    Amidases
  3.    Transferase
  4.    Aldo-keto-reductases
 Discuss Question
Answer: Option C. -> Transferase
Answer: (c).Transferase
Question 22. Which coenzyme is synthesized in the 1st step of the formation of Glucuronide?
  1.    Uridine triphosphate
  2.    Uridine-5’-diphosphate-alpha-D-glucuronic acid
  3.    UDP-glucose
  4.    Glucuronide
 Discuss Question
Answer: Option B. -> Uridine-5’-diphosphate-alpha-D-glucuronic acid
Answer: (b).Uridine-5’-diphosphate-alpha-D-glucuronic acid
Question 23. The phase II reactions are detoxification pathways.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 24. Which of the following is not a characteristic of the moieties that are transferred to the substrate in phase II reactions?
  1.    Simple endogenous molecules are transferred
  2.    Large molecular sized groups are attached
  3.    Strong polar groups are attached
  4.    Strong nonpolar groups are attached
 Discuss Question
Answer: Option D. -> Strong nonpolar groups are attached
Answer: (d).Strong nonpolar groups are attached
Question 25. Which of the following statement is false?
  1.    D-glucuronic acid is easily available
  2.    Several functional groups can be easily linked with the D-glucuronic acid
  3.    Conjugation with D-glucuronic acid occurs to a high degree
  4.    Whole animal kingdom have the common ability to produce D-glucuronic acid
 Discuss Question
Answer: Option D. -> Whole animal kingdom have the common ability to produce D-glucuronic acid
Answer: (d).Whole animal kingdom have the common ability to produce D-glucuronic acid
Question 26. What is the name of the process where the enzyme amount is decreased due to a decrease in enzyme synthesis?
  1.    Altered physiology
  2.    Repression
  3.    Non-competitive inhibition
  4.    Competitive inhibition
 Discuss Question
Answer: Option B. -> Repression
Answer: (b).Repression
Question 27. What is the name of the process where due to nutritional deficiency an enzyme content is decreased?
  1.    Altered physiology
  2.    Repression
  3.    Non-competitive inhibition
  4.    Competitive inhibition
 Discuss Question
Answer: Option A. -> Altered physiology
Answer: (a).Altered physiology
Question 28. Differences observed in metabolism of drug among different races is known as ______________
  1.    Pharmacogenetics
  2.    Ethnic variations
  3.    Discontinues variation
  4.    Polygenic control
 Discuss Question
Answer: Option B. -> Ethnic variations
Answer: (b).Ethnic variations
Question 29. What is polygenic control of drugs?
  1.    Drug controlling seen in an individual
  2.    Drug controlling seen in twins
  3.    Drug controlling seen in between different species
  4.    Drug controlling seen in a particular population
 Discuss Question
Answer: Option B. -> Drug controlling seen in twins
Answer: (b).Drug controlling seen in twins
Question 30. Which one of the following is not an environmental agent to decrease drug metabolizing ability?
  1.    DDT
  2.    Cigarette smoke
  3.    Organophosphate insecticides
  4.    Methacholine
 Discuss Question
Answer: Option D. -> Methacholine
Answer: (d).Methacholine

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