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Total Questions : 101 | Page 6 of 11 pages
Question 51. What is Ubiquitin?
  1.    Protein kinase
  2.    Protease
  3.    Component of the electron transport system
  4.    Protein that tags another protein for proteolysis
 Discuss Question
Answer: Option D. -> Protein that tags another protein for proteolysis
Answer: (d).Protein that tags another protein for proteolysis
Question 52. Which property of p53 enables it to prevent the development of cancer?
  1.    It is a transcription factor that causes protein production which stimulates the cell cycle
  2.    It prevents replication of cells with damaged DNA
  3.    It prevents cells from triggering apoptosis
  4.    It stimulates synthesis of DNA repair enzymes that replace telomere sequence lost during cell division
 Discuss Question
Answer: Option B. -> It prevents replication of cells with damaged DNA
Answer: (b).It prevents replication of cells with damaged DNA
Question 53. The characteristic of malignant other than a benign tumor is?
  1.    Undergoes metastasis
  2.    Develops blood supply
  3.    Cell divides an unlimited number of times
  4.    Grows without needing a growth signal
 Discuss Question
Answer: Option A. -> Undergoes metastasis
Answer: (a).Undergoes metastasis
Question 54. Migration of cancerous cells from the site of origin to other part of the body forming secondary tumors is called ___________
  1.    Diapedesis
  2.    Metastasis
  3.    Proliferation
  4.    Apoptosis
 Discuss Question
Answer: Option B. -> Metastasis
Answer: (b).Metastasis
Question 55. Which of the following about Rb tumor suppressor protein is correct?
  1.    It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received
  2.    It is activated when phosphorylated by Cdk
  3.    It is a transcription factor
  4.    When a mitogenic signal is received, it binds the transcription factor E2F and thus stimulates the cell to enter S phase
 Discuss Question
Answer: Option A. -> It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received
Answer: (a).It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received
Question 56. The mutation which cannot give rise to an oncogene?
  1.    Addition or deletion of a base producing a nonsense message and an inactive protein product
  2.    A point mutation changing just one amino acid in protein product
  3.    A translocation, putting gene under control of strong promoter producing over expression
  4.    A point mutation producing stop codon, premature termination
 Discuss Question
Answer: Option A. -> Addition or deletion of a base producing a nonsense message and an inactive protein product
Answer: (a).Addition or deletion of a base producing a nonsense message and an inactive protein product
Question 57. The information which is represented by a signal is detected by specific receptors and converted to a cellular response; this conversion is called _____________
  1.    Signal amplification
  2.    Signal transversion
  3.    Signal transduction
  4.    Signal integration
 Discuss Question
Answer: Option C. -> Signal transduction
Answer: (c).Signal transduction
Question 58. Signal molecule fits the binding site on its complementary receptor called as _____________
  1.    Specificity
  2.    Amplification
  3.    Integration
  4.    Cooperativity
 Discuss Question
Answer: Option A. -> Specificity
Answer: (a).Specificity
Question 59. Regulatory outcome results from integrated input from both receptors is in _____________
  1.    Specificity
  2.    Amplification
  3.    Adaptation
  4.    Integration
 Discuss Question
Answer: Option D. -> Integration
Answer: (d).Integration
Question 60. Number of affected molecules increases geometrically in an enzyme cascade in _____________
  1.    Specificity
  2.    Amplification
  3.    Adaptation
  4.    Integration
 Discuss Question
Answer: Option B. -> Amplification
Answer: (b).Amplification

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