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MCQs

Total Questions : 101 | Page 8 of 11 pages
Question 71. Which out of the following is not involved in signal transduction by β-adrenergic receptor pathway?
  1.    GTP
  2.    ATP
  3.    cAMP
  4.    cGMP
 Discuss Question
Answer: Option C. -> cAMP
Answer: (c).cAMP
Question 72. Which of the following directly phosphorylate tyrosines to start a kinase protein enzymatic cascade?
  1.    Receptor tyrosine kinase
  2.    Receptor guanylyl cyclases
  3.    Receptor serine kinase
  4.    Receptor threonine kinase
 Discuss Question
Answer: Option A. -> Receptor tyrosine kinase
Answer: (a).Receptor tyrosine kinase
Question 73. The specificity of signaling pathways does not include ___________
  1.    Migration of signal proteins into membrane rafts
  2.    Assembly of large multiprotein complexes
  3.    Phosphorylation of target proteins at Ser, Thr/Tyr residues
  4.    Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet
 Discuss Question
Answer: Option D. -> Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet
Answer: (d).Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet
Question 74. Which of the following is involved in extrinsic cell death pathway?
  1.    Heterotrimeric G protein complex
  2.    TRADD
  3.    IRS-1
  4.    Protein-kinase A
 Discuss Question
Answer: Option B. -> TRADD
Answer: (b).TRADD
Question 75. PTB domains bind to ___________
  1.    Phosphorylated tyrosine
  2.    Phosphoryated threonine
  3.    Phosphorylated serine
  4.    Phosphorylated cysteine
 Discuss Question
Answer: Option A. -> Phosphorylated tyrosine
Answer: (a).Phosphorylated tyrosine
Question 76. Scaffold protein in insulin signal transduction ___________
  1.    KSR
  2.    IRS-1
  3.    MEKK1
  4.    AKAP
 Discuss Question
Answer: Option B. -> IRS-1
Answer: (b).IRS-1
Question 77. Which of the following are stimulated to become membrane associated upon binding of insulin to the insulin receptor?
  1.    PH-domain
  2.    PTB
  3.    SH₃
  4.    SH₂
 Discuss Question
Answer: Option A. -> PH-domain
Answer: (a).PH-domain
Question 78. Which of the following converts GTP to cGMP to start its enzymatic cascade?
  1.    Receptor guanylyl cyclase
  2.    Receptor adenylyl cyclase
  3.    Calmodulin
  4.    Protein kinase-A
 Discuss Question
Answer: Option A. -> Receptor guanylyl cyclase
Answer: (a).Receptor guanylyl cyclase
Question 79. Which of the following is involved in proline rich motif binding?
  1.    SH2
  2.    SH3
  3.    PTB
  4.    PH
 Discuss Question
Answer: Option B. -> SH3
Answer: (b).SH3
Question 80. Which of the following is involved in phospho-tyrosine binding?
  1.    SH2
  2.    SH3
  3.    PTB
  4.    PH
 Discuss Question
Answer: Option A. -> SH2
Answer: (a).SH2

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