Question
What is the biggest disadvantage of plasmids?
Answer: Option C
:
C
Since the size of the plasmid has to remain smaller than the cellular DNA, the gene that is intended to be inserted into the plasmid cannot be very large in size. Maximum size permissible in a plasmid vector is 7 Kbp (kilobase pair).
However, there are certain genes that are much longer than 7 kilobase pairs. Plasmids cannot be used when such large genes need to be transferred into a host cell.
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:
C
Since the size of the plasmid has to remain smaller than the cellular DNA, the gene that is intended to be inserted into the plasmid cannot be very large in size. Maximum size permissible in a plasmid vector is 7 Kbp (kilobase pair).
However, there are certain genes that are much longer than 7 kilobase pairs. Plasmids cannot be used when such large genes need to be transferred into a host cell.
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