Questions and answers for exam Preparation

MCQs

Total Questions : 150 | Page 14 of 15 pages

Question 131. The overall goal of pair wise sequence alignment is to find the best pairing of two sequences, such that there is maximum correspondence among residues.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 132. In local alignment, the two sequences to be aligned cannot be of unequal lengths.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 133. Alignment algorithms, both global and local, are fundamentally similar and only differ in the optimization strategy used in aligning similar residues.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 134. When the two sequences have substantial regions of similarity, many dots line up to form contiguous _______ lines.

crossings on
horizontal
diagonal
vertical

Discuss Question

Answer: Option C. -> diagonal
Answer: (c).diagonal

Question 135. In a dot matrix, two sequences to be compared are written in the _____________ of the matrix.

horizontal and vertical axes
2 parallel horizontal axes
2 parallel vertical axes
horizontal axis (one preceding another)

Discuss Question

Answer: Option A. -> horizontal and vertical axes
Answer: (a).horizontal and vertical axes

Question 136. Emotif uses which databases for alignment of sequences?

BLOCKS and PRINTS databases
PROSITE
BLOCKS
PRINTS

Discuss Question

Answer: Option A. -> BLOCKS and PRINTS databases
Answer: (a).BLOCKS and PRINTS databases

Question 137. Which of the following is not a characteristic of exact matches in regular expression?

There must be a strict match of sequence patterns
Any variations in the query sequence from the predefined patterns are not allowed
Provide more permissive matching by allowing more flexible matching of residues of similar biochemical properties
Searching a motif database using this approach results in either a match or non-match

Discuss Question

Answer: Option C. -> Provide more permissive matching by allowing more flexible matching of residues of similar biochemical properties
Answer: (c).Provide more permissive matching by allowing more flexible matching of residues of similar biochemical properties

Question 138. While analysing motif sequences, what is the major disadvantageous feature of PROSITE?

The database constructs profiles to complement some of the sequence patterns
The functional information of these patterns is primarily based on published literature
Some of the sequence patterns are too short to be specific
Lack of specificity about probability and variation and relation between them

Discuss Question

Answer: Option C. -> Some of the sequence patterns are too short to be specific
Answer: (c).Some of the sequence patterns are too short to be specific

Question 139. Which of the following is not a characteristic of Fuzzy or approximate matches in regular expression?

This method is able to include more variant forms of a motif with a conserved function
the rule of matching is based on observations, not actual assumptions
with the more relaxed matching, there is increase of the noise level and false positives
the rule of matching is based on assumptions not actual observations

Discuss Question

Answer: Option B. -> the rule of matching is based on observations, not actual assumptions
Answer: (b).the rule of matching is based on observations, not actual assumptions

Question 140. What does this representation mean- R.L.[EQD]?

An arginine- Amino acid- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine
An arginine- Leucine- Either Apartic acid, glutamic acid or glutamine
An arginine- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine
An arginine- Leucine- Apartic acid and glutamic acid and glutamine

Discuss Question

Answer: Option A. -> An arginine- Amino acid- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine
Answer: (a).An arginine- Amino acid- Leucine- Amino acid- Either Apartic acid, glutamic acid or glutamine