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MCQs

Total Questions : 150 | Page 12 of 15 pages
Question 111. Motifs that can form α/β horseshoes conformation are rich with which protein residue?
  1.    Proline
  2.    Arginine
  3.    Valine
  4.    Leucine
 Discuss Question
Answer: Option D. -> Leucine
Answer: (d).Leucine
Question 112. Which of the following wrongly describes protein domains?
  1.    They are made up of one secondary structure
  2.    Defined as independently foldable units
  3.    They are stable structures as compared to motifs
  4.    They are separated by linker regions
 Discuss Question
Answer: Option A. -> They are made up of one secondary structure
Answer: (a).They are made up of one secondary structure
Question 113. Which of the following is not the function of Short Linear Motifs?
  1.    Irreversible cleavage of the peptide at the SLiM
  2.    Reversible cleavage of the peptide at the SLiM
  3.    Moiety addition at targeted sites on SLiM
  4.    Structural modifications of the peptide backbone
 Discuss Question
Answer: Option A. -> Irreversible cleavage of the peptide at the SLiM
Answer: (a).Irreversible cleavage of the peptide at the SLiM
Question 114. The protein structural motif domain- helix loop helix are contained by all of the following except ________
  1.    Scleraxis
  2.    Neurogenins
  3.    Transcription Factor 4
  4.    Leucine zipper
 Discuss Question
Answer: Option D. -> Leucine zipper
Answer: (d).Leucine zipper
Question 115. In the zinc finger, which residues in this sequence motif form ligands to a zinc ion?
  1.    Cysteine and histidine
  2.    Cysteine and arginine
  3.    Histidine and proline
  4.    Histidine and arginine
 Discuss Question
Answer: Option A. -> Cysteine and histidine
Answer: (a).Cysteine and histidine
Question 116. On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________
  1.    Gumbel equal value distribution
  2.    Gumbel extreme value distribution
  3.    Gumbel end value distribution
  4.    Gumbel distribution
 Discuss Question
Answer: Option B. -> Gumbel extreme value distribution
Answer: (b).Gumbel extreme value distribution
Question 117. Waterman, in1989, provided a set of means and standard deviations of global alignment scores between random DNA sequences, using mismatch and gap penalties that produce a linear increase in score with _______ a distinguishing feature of global alignments.
  1.    alignment score
  2.    sequence score
  3.    sequence length
  4.    scoring system
 Discuss Question
Answer: Option C. -> sequence length
Answer: (c).sequence length
Question 118. When random or unrelated sequences are compared using a global alignment method, they can have ____________ reflecting the tendency of the global algorithm to match as many characters as possible.
  1.    very low scores
  2.    very high scores
  3.    moderate scores
  4.    low scores
 Discuss Question
Answer: Option B. -> very high scores
Answer: (b).very high scores
Question 119. Which of the following are not related to Needleman-Wunsch alignment algorithm?
  1.    Global alignment programs use this algorithm
  2.    The output is a positive number
  3.    Small changes in the scoring system can produce a different alignment
  4.    Changes in the scoring system can produce the same alignment
 Discuss Question
Answer: Option D. -> Changes in the scoring system can produce the same alignment
Answer: (d).Changes in the scoring system can produce the same alignment
Question 120. The statistical analysis of alignment scores is much better understood for ________ than for _______
  1.    global alignments, local alignments
  2.    local alignments, global alignments
  3.    global alignments, any other alignment method
  4.    Needleman-Wunsch alignment, Smith-Waterman alignment
 Discuss Question
Answer: Option B. -> local alignments, global alignments
Answer: (b).local alignments, global alignments

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