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MCQs

Total Questions : 15 | Page 1 of 2 pages
Question 1.  Beta pleated sheets are examples of protein's
  1.    primary structure
  2.    secondary structure
  3.    tertiary structure
  4.    quaternary structure
 Discuss Question
Answer: Option B. -> secondary structure
Question 2.  BRACl, an inherited form of breast cancer, regulates cell division by
  1.    binding to a DNA sequence
  2.    complexing with cyclins
  3.    binding to the cell outer membrane
  4.    binding to the protein RAD 51 which repairs DNA damage
 Discuss Question
Answer: Option D. -> binding to the protein RAD 51 which repairs DNA damage
Question 3.  Marfan's syndrome is thought to be a mutation affecting
  1.    hemoglobin synthesis
  2.    collagen synthesis
  3.    metabolism of homogentisic acid
  4.    insufficient thyroid production
 Discuss Question
Answer: Option B. -> collagen synthesis
Question 4.  Individuals with PKU disease are mentally retarded unless
  1.    phenylalanine in the diet is restricted
  2.    tyrosine in the diet is restricted
  3.    homogentisic acid in the diet is restricted
  4.    none of the above
 Discuss Question
Answer: Option A. -> phenylalanine in the diet is restricted
Question 5.  Cyclins are proteins that
  1.    regulate ability of cells to invade tissue
  2.    regulate passage from one stage of cell division to another
  3.    regulate apoptosis of damaged cells
  4.    none of the above
 Discuss Question
Answer: Option B. -> regulate passage from one stage of cell division to another
Question 6.  Metastasis involves
  1.    ability of cells to dissolve cellular matrix
  2.    metalloprotein levels
  3.    decreased levels of proteins that regulate metalloproteins
  4.    all of the above
 Discuss Question
Answer: Option D. -> all of the above
Question 7.  Signal sequences are part of a protein that
  1.    signal folding of the protein
  2.    signal the protein synthesis on the ribosomes is ended
  3.    transport proteins to other sites within the cell
  4.    refold proteins in prion-associated diseases
 Discuss Question
Answer: Option C. -> transport proteins to other sites within the cell
Question 8.  Over 50% of common cancers are associated with damage to a protein, p53. This protein
  1.    is a cyclin
  2.    is a tumor supressor
  3.    is an oncogene
  4.    regulates apoptosis
 Discuss Question
Answer: Option B. -> is a tumor supressor
Question 9.  Protein folding is
  1.    automatic, mediated by the protein itself
  2.    mediated by other proteins called chaperones
  3.    mediated by the ribosomes
  4.    none of the above
 Discuss Question
Answer: Option B. -> mediated by other proteins called chaperones
Question 10. . Sickle cell disease is due to
  1.    a mutation in the beta chain of Hb
  2.    a mutation in the alpha chain of Hb
  3.    infection with a parasite
  4.    none of the above
 Discuss Question
Answer: Option A. -> a mutation in the beta chain of Hb

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