Questions and answers for exam Preparation

MCQs

Total Questions : 62 | Page 5 of 7 pages

Question 41. What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?

3ml/sec
0.3ml/sec
1ml/sec
1.3ml/sec

Discuss Question

Answer: Option D. -> 1.3ml/sec
Answer: (d).1.3ml/sec

Question 42. How do you calculate the rate of excretion by kidneys?

Rate of filtration – the rate of secretion – Rate of absorption
Rate of filtration + rate of secretion – Rate of absorption
Rate of filtration + rate of secretion + Rate of absorption
Rate of filtration – the rate of secretion + Rate of absorption

Discuss Question

Answer: Option B. -> Rate of filtration + rate of secretion – Rate of absorption
Answer: (b).Rate of filtration + rate of secretion – Rate of absorption

Question 43. “Cascade lantentiation” concept takes into account which kind of prodrugs?

Mixed type prodrugs
Pro-prodrugs
Bioprecursors
Carrier linked prodrugs

Discuss Question

Answer: Option B. -> Pro-prodrugs
Answer: (b).Pro-prodrugs

Question 44. What is a prodrug?

An excipient which helps in creating the environment for the drug-dissolving
Chemically drug precursor
Excipient of drug formulation
A drug which is used by professionals

Discuss Question

Answer: Option B. -> Chemically drug precursor
Answer: (b).Chemically drug precursor

Question 45. Which of the following is the correct characteristic of bio precursors/ metabolic precursors?

The inert carrier is attached through a chemical bond
There is no inert carrier
There is a change in pH while the formulation
The active drug is converted to its inert form chemically

Discuss Question

Answer: Option D. -> The active drug is converted to its inert form chemically
Answer: (d).The active drug is converted to its inert form chemically

Question 46. Prodrugs with two active compounds are known as ___________

Mixed type prodrugs
Pro-prodrugs
Bioprecursors
Mutual prodrug

Discuss Question

Answer: Option D. -> Mutual prodrug
Answer: (d).Mutual prodrug

Question 47. Which of the following is not a characteristic of ideal prodrug?

Should rapidly transform, chemically and enzymatically forming the active product
Should have intrinsic pharmacological activity
The vapour pressure should be less and evaporate easily
Apart from an active product, other metabolic fragments should be nontoxic

Discuss Question

Answer: Option C. -> The vapour pressure should be less and evaporate easily
Answer: (c).The vapour pressure should be less and evaporate easily

Question 48. Which is the earliest discovered prodrug?