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MCQs

Total Questions : 62 | Page 2 of 7 pages
Question 11. What is the equation for biliary clearance?
  1.    No such equation is there
  2.    Biliary excretion rate/ plasma drug concentration
  3.    Plasma drug concentration / biliary excretion rate
  4.    Plasma drug concentration / Bile flow * biliary drug concentration
 Discuss Question
Answer: Option B. -> Biliary excretion rate/ plasma drug concentration
Answer: (b).Biliary excretion rate/ plasma drug concentration
Question 12. Which compounds are excreted through the lungs?
  1.    Lipophilic
  2.    Gaseous
  3.    Liquid and hydrophilic
  4.    Solid less than 100 Dalton
 Discuss Question
Answer: Option B. -> Gaseous
Answer: (b).Gaseous
Question 13. For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?
  1.    1.50 ml/mm
  2.    1.75 ml/mm
  3.    2.75 ml/mm
  4.    3 ml/mm
 Discuss Question
Answer: Option B. -> 1.75 ml/mm
Answer: (b).1.75 ml/mm
Question 14. What is the mechanism of drug excretion for skin excretion?
  1.    Active secretion
  2.    Glomerular secretion
  3.    Passive diffusion
  4.    Passive reabsorption
 Discuss Question
Answer: Option C. -> Passive diffusion
Answer: (c).Passive diffusion
Question 15. What is the pH of the milk secreted by human mothers?
  1.    6.4-7.6
  2.    5.4-6.6
  3.    7-8
  4.    6-7
 Discuss Question
Answer: Option A. -> 6.4-7.6
Answer: (a).6.4-7.6
Question 16. Drugs of molecular range 300-500 Dalton will be excreted out by glomerulus.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 17. Which of the following is not a physicochemical factor of drug that can affect the renal excretion?
  1.    Molecular size
  2.    Disintegration rate
  3.    pKa of the drug
  4.    Lipid solubility
 Discuss Question
Answer: Option B. -> Disintegration rate
Answer: (b).Disintegration rate
Question 18. Clearance is inversely related to volume of distribution.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 19. Which one is the correct equation to calculate the fraction of unbound drug in plasma?
  1.    Concentration of unbound drug in plasma / total plasma concentration of drug
  2.    Total plasma concentration of drug / Concentration of unbound drug in plasma
  3.    1/Concentration of unbound drug in plasma
  4.    1/total plasma concentration of drug
 Discuss Question
Answer: Option A. -> Concentration of unbound drug in plasma / total plasma concentration of drug
Answer: (a).Concentration of unbound drug in plasma / total plasma concentration of drug
Question 20. Which drugs cannot be filtered through glomerulus?
  1.    Drugs bound to plasma proteins
  2.    Unbound
  3.    Free drug
  4.    Below molecular weight of 300 Dalton
 Discuss Question
Answer: Option A. -> Drugs bound to plasma proteins
Answer: (a).Drugs bound to plasma proteins

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