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MCQs

Total Questions : 62 | Page 1 of 7 pages
Question 1. Which of the following will be the pharmacokinetic application of prodrugs?
  1.    Improvement of taste
  2.    Improvement of odour
  3.    Site-specific drug delivery
  4.    Reduction in GI irritation
 Discuss Question
Answer: Option C. -> Site-specific drug delivery
Answer: (c).Site-specific drug delivery
Question 2. A liquid with high vapour pressure has a strong odour.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 3. How improvement of a drug in case of taste is done?
  1.    Injecting the drug so no taste related problems
  2.    Reducing the drug solubility in the saliva
  3.    Lower affinity for the taste receptors and making the drug sweet
  4.    Reducing drug solubility in saliva and lower affinity for taste receptors
 Discuss Question
Answer: Option D. -> Reducing drug solubility in saliva and lower affinity for taste receptors
Answer: (d).Reducing drug solubility in saliva and lower affinity for taste receptors
Question 4. Which one of the following will be an example of changing the physical form of the drug to get a prodrug?
  1.    Ethyl mercaptan to 1,3-Diesters
  2.    Trichloroethanol to p-Acetamidobenzene ester
  3.    Ethyl mercaptan to phthalate esters
  4.    Chloramphenicol to palmitate ester
 Discuss Question
Answer: Option A. -> Ethyl mercaptan to 1,3-Diesters
Answer: (a).Ethyl mercaptan to 1,3-Diesters
Question 5. No drug cause damage to the gastric mucosa.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option B. -> False
Answer: (b).False
Question 6. Which of the following will not be a limitation for prodrug design?
  1.    Formation of toxic product
  2.    An inert carrier can be cleaved off forming toxic product
  3.    Product cleaving off before reaching the target site
  4.    The cleaving of the carrier is also site-specific
 Discuss Question
Answer: Option D. -> The cleaving of the carrier is also site-specific
Answer: (d).The cleaving of the carrier is also site-specific
Question 7. How to prevent hepatic first-pass metabolism for corticosteroids?
  1.    Providing intravenously
  2.    Providing orally
  3.    Form esters and ether products
  4.    By enhancing lipophilicity
 Discuss Question
Answer: Option C. -> Form esters and ether products
Answer: (c).Form esters and ether products
Question 8. Which one of the following is the principal organ for drug excretion?
  1.    Lungs
  2.    Liver
  3.    Kidneys
  4.    Sweat glands
 Discuss Question
Answer: Option C. -> Kidneys
Answer: (c).Kidneys
Question 9. What is the molecular weight cut off for biliary excretion?
  1.    Less than 300 Dalton
  2.    More than 300 Dalton
  3.    Less than 200 Dalton
  4.    More than 200 Dalton
 Discuss Question
Answer: Option B. -> More than 300 Dalton
Answer: (b).More than 300 Dalton
Question 10. Compounds excreted in bile is classified into 3 categories. Which one of the following does not come under the categories?
  1.    Drugs with bile/plasma concentration ratio approximately 1
  2.    Drugs with bile/plasma concentration ratio between 10-1000
  3.    Drugs with bile/plasma concentration ratio of less than 1
  4.    Drugs with bile/plasma concentration ratio above 1000
 Discuss Question
Answer: Option D. -> Drugs with bile/plasma concentration ratio above 1000
Answer: (d).Drugs with bile/plasma concentration ratio above 1000

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