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Total Questions : 46 | Page 5 of 5 pages
Question 41. . A nonsense mutation introduced into the DNA sequence of a gene may
  1.    cause premature termination of the mRNA
  2.    shorten the length of the protein encoded by the gene
  3.    have no effect on the transcript or protein made
  4.    cause a shift in reading frame
 Discuss Question
Answer: Option B. -> shorten the length of the protein encoded by the gene
Question 42. . Which of these mechanisms for thymine dimers repair lead to mutations?
  1.    Excision repair
  2.    Photoreactivation
  3.    SOS repair
  4.    Never leads to mutation
 Discuss Question
Answer: Option C. -> SOS repair
Question 43. . The promoter on an expression vector used to overproduce proteins in bacteria is
  1.    a bacterial promoter
  2.    expressed both in bacteria and mammalian cells
  3.    not a regulated promoter
  4.    the natural promoter of the gene being cloned
 Discuss Question
Answer: Option A. -> a bacterial promoter
Question 44. . Frame shift mutation may occur as a result of
  1.    formation of a thymine-dimer
  2.    deamination of cytosine to uracil
  3.    conversion of guanine to xanthine
  4.    none of the above
 Discuss Question
Answer: Option D. -> none of the above
Question 45. . Thymine dimers are directly repaired with the help of visible light by process known as
  1.    phosphorylation
  2.    excision repair
  3.    photosynthesis
  4.    photoreactivation
 Discuss Question
Answer: Option D. -> photoreactivation
Question 46. . Differentiation of four different bases in automated sequencing systems is that each base has
  1.    different radioactive tag
  2.    cytosine at start
  3.    unique antibody bound to it
  4.    distinctive fluorescent tag
 Discuss Question
Answer: Option D. -> distinctive fluorescent tag

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