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MCQs

Total Questions : 46 | Page 2 of 5 pages
Question 11. Which of the following mutation affects only a single nucleotide?
  1.    Aerial mutation
  2.    Site mutation
  3.    Regional mutation
  4.    Point mutation
 Discuss Question
Answer: Option D. -> Point mutation
Question 12. The DNA sequences of rRNA genes can be used to
  1.    obtain a tentative identification of a new microorganism
  2.    predict whether a bacteria will be gram-positive or gram-negative
  3.    assess relatedness of eukaryotes but not prokaryotes
  4.    predict the pulsed field gel pattern of a microorganism
 Discuss Question
Answer: Option A. -> obtain a tentative identification of a new microorganism
Question 13. A mutagen is defined as
  1.    an inhibitor of gene modification
  2.    an enzyme that repairs mutations
  3.    a chemical or physical agent that induces mutations
  4.    a molecule which stabilizes DNA thus prevents mutations from occurring
 Discuss Question
Answer: Option C. -> a chemical or physical agent that induces mutations
Question 14. A nonsense mutation introduced into the DNA sequence of a gene may
  1.    have no effect on the transcript or protein made
  2.    shorten the length of the protein encoded by the gene
  3.    cause a shift in reading frame
  4.    cause premature termination of the mRNA
 Discuss Question
Answer: Option B. -> shorten the length of the protein encoded by the gene
Question 15. When mutations involve vital functions so that the mutants are nonviable, it is a
  1.    transversion
  2.    lethal mutation
  3.    none of these
  4.    nonsense mutation
 Discuss Question
Answer: Option B. -> lethal mutation
Question 16. Frame shift mutation may occur as a result of
  1.    None of these
  2.    formation of a thymine-dimer
  3.    conversion of guanine to xanthine
  4.    deamination of cytosine to uracil
 Discuss Question
Answer: Option A. -> None of these
Question 17. Differentiation of four different bases in automated sequencing systems is that each base has
  1.    distinctive fluorescent tag
  2.    cytosine at start
  3.    different radioactive tag
  4.    unique antibody bound to it
 Discuss Question
Answer: Option A. -> distinctive fluorescent tag
Question 18. Which of these mechanisms for thymine dimers repair lead to mutations?
  1.    Excision repair
  2.    Photoreactivation
  3.    Never leads to mutation
  4.    SOS repair
 Discuss Question
Answer: Option D. -> SOS repair
Question 19. The promoter on an expression vector used to overproduce proteins in bacteria is
  1.    expressed both in bacteria and mammalian cells
  2.    the natural promoter of the gene being cloned
  3.    a bacterial promoter
  4.    not a regulated promoter
 Discuss Question
Answer: Option C. -> a bacterial promoter
Question 20. Thymine dimers are directly repaired with the help of visible light by process known as
  1.    phosphorylation
  2.    photoreactivation
  3.    excision repair
  4.    photosynthesis
 Discuss Question
Answer: Option B. -> photoreactivation

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