Questions and answers for exam Preparation

MCQs

Total Questions : 80 | Page 7 of 8 pages

Question 61. Analysis of MSAs for conserved blocks of sequence leads to production of the position-specific scoring matrix.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 62. Two considerations arise in trying to tune the PSSM so that it adequately represents the training sequences. Which of the following is not their description?

If a given column in 20 sequences has only isoleucine, it is not very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function
If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function
If the number of sequences with the found motif is large and reasonably diverse, the sequences represent a good statistical sampling of all sequences that are ever likely to be found with that same motif
Another column in the motif from the 20 sequences may have several amino acids, and some amino acids may not be represented at all

Discuss Question

Answer: Option B. -> If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function
Answer: (b).If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function

Question 63. The quality and quantity of information provided by the PSSM also varies for ________ in the motif.

each row
each column
rows and columns
neither the rows nor the columns

Discuss Question

Answer: Option B. -> each column
Answer: (b).each column

Question 64. If a good sampling of sequences is _______ the number of sequences is _________ and the motif structure is ________ it should, in principle, be possible to obtain frequencies highly representative of the same motif in other sequences also.

available, sufficiently large, not too complex
unavailable, sufficiently large, not too complex
unavailable, sufficiently small, not too complex
available, sufficiently large, too complex

Discuss Question

Answer: Option A. -> available, sufficiently large, not too complex
Answer: (a).available, sufficiently large, not too complex

Question 65. If the data set is _______ then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif.

small, distinct
small, almost identical
large, almost identical
large, distinct

Discuss Question

Answer: Option B. -> small, almost identical
Answer: (b).small, almost identical

Question 66. Even if many pseudocounts are added in comparison to real sequence counts, the amino acid frequencies will not have any effect or influence.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 67. Which of the following is not a feature of editors and formatters?

provision for displaying the sequence on a color monitor with residue colors to aid in a clear visual representation of the alignment
recognition of the multiple sequence format that was output by the MSA (Multiple Sequence Alignment) program
maintenance of the alignment in a suitable format when the editing is completed
disallowing shading conserved residues in the alignment

Discuss Question

Answer: Option D. -> disallowing shading conserved residues in the alignment
Answer: (d).disallowing shading conserved residues in the alignment

Question 68. GDE (Genetic Data Environment) provides a general interface on UNIX machines for sequence analysis, sequence alignment editing, and display.