Questions and answers for exam Preparation

MCQs

Total Questions : 80 | Page 2 of 8 pages

Question 11. In the intermediate steps of EM algorithm, the number of each base in each column is determined and then converted to fractions.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 12. For the 10-residue DNA sequence example, there are _______ possible starting sites for a 20-residue-long site.

Discuss Question

Answer: Option C. -> 81
Answer: (c).81

Question 13. Which of the following about the Gibbs sampler is untrue?

It is a statistical method for finding motifs in sequences
It is dissimilar to the principle of the EM method
It searches for the statistically most probable motifs
It can find the optimal width and number of given motifs in each sequence

Discuss Question

Answer: Option B. -> It is dissimilar to the principle of the EM method
Answer: (b).It is dissimilar to the principle of the EM method

Question 14. An alternative method is to produce an odds scoring matrix calculated by dividing each base frequency by the background frequency of that base.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 15. Which of the following about MEME is untrue?

It is a Web resource for performing local MSAs (Multiple Sequence Alignment) by the above expectation maximization method is the program MEME
It stands for Multiple EM for Motif Elicitation
It was developed at developed at the University of California at San Diego Supercomputing Center
The Web page has multiple versions for searching blocks by an EM algorithm

Discuss Question

Answer: Option D. -> The Web page has multiple versions for searching blocks by an EM algorithm
Answer: (d).The Web page has multiple versions for searching blocks by an EM algorithm

Question 16. Iterative methods include repeatedly realigning subgroups of the sequences and then by aligning these subgroups into a local alignment of all of the sequences.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 17. Which of the following is incorrect regarding PRRP?

The program PRRP uses iterative methods to produce an alignment
An initial pair-wise alignment is made to predict a tree
Only one cycle is performed
The whole process is repeated until there is no further increase in the alignment score

Discuss Question

Answer: Option C. -> Only one cycle is performed
Answer: (c).Only one cycle is performed

Question 18. In the program DIALIGN, pairs of sequences are aligned to locate aligned regions that do not include gaps, much like continuous diagonals in a dot matrix plot.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 19. The Genetic Algorithm method has been recently adapted for MSA(Multiple Sequence Alignment) by Corpet (1998).

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 20. An approach for obtaining a higher-scoring MSA (Multiple Sequence Alignment) by rearranging an existing alignment uses a probability approach called simulated annealing.