Questions and answers for exam Preparation

MCQs

Total Questions : 80 | Page 5 of 8 pages

Question 41. Progressive alignment methods use the dynamic programming method to build an MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 42. Which of the following is untrue about CLUSTAL program?

CLUSTAL performs a global-multiple sequence alignment by a different method than MSA (Multiple Sequence Alignment)
The initial heuristic alignment obtained by MSA is calculated in a different way
The initial step includes performing pair-wise alignments of all of the sequences
The intermediate step includes use the alignment scores to produce a phylogenetic tree

Discuss Question

Answer: Option B. -> The initial heuristic alignment obtained by MSA is calculated in a different way
Answer: (b).The initial heuristic alignment obtained by MSA is calculated in a different way

Question 43. Progenitor sequences represented by the ______ branches of the tree are derived by alignment of the _______ sequences.

outer, outermost
inner, outermost
inner, innermost
outer, innermost

Discuss Question

Answer: Option B. -> inner, outermost
Answer: (b).inner, outermost

Question 44. The CLUSTALX provides a graphic interface.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 45. CLUSTALW is a more recent version of CLUSTAL with the W standing for ________

weakening
winding
weighting
wiping

Discuss Question

Answer: Option C. -> weighting
Answer: (c).weighting

Question 46. Related sequences are identified through the database similarity searching and as the process generates multiple matching sequence pairs, it is often necessary to convert the numerous pair wise alignments into a single alignment.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 47. The scoring function for multiple sequence alignment is based on the concept of sum of pairs (SP).

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 48. There is a unique advantage of multiple sequence alignment because it reveals more biological information than many pair wise alignments can.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 49. Which of the following scores are not considered while calculating the SP scores?

All possible pair wise matches
All possible mismatches
All possible gap costs
Number of gap penalties

Discuss Question

Answer: Option D. -> Number of gap penalties
Answer: (d).Number of gap penalties

Question 50. Which of the following cannot be related to multiple sequence alignment?

Many conserved and functionally critical amino acid residues can be identified in a protein multiple alignment
Multiple sequence alignment is also an essential prerequisite to carrying out phylogenetic analysis of sequence families and prediction of protein secondary and tertiary structures
Multiple sequence alignment also has applications in designing degenerate polymerase chain reaction (PCR) primers based on multiple related sequences
This method does not contribute much to degenerate polymerase chain reaction (PCR) primers creation

Discuss Question

Answer: Option D. -> This method does not contribute much to degenerate polymerase chain reaction (PCR) primers creation
Answer: (d).This method does not contribute much to degenerate polymerase chain reaction (PCR) primers creation