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11th And 12th > Biology

MOLECULAR BASIS OF INHERITANCE MCQs

Total Questions : 75 | Page 1 of 8 pages
Question 1.


The number of codons coding for the 20 known amino acids is


  1.     64
  2.     60
  3.     61
  4.     67
 Discuss Question
Answer: Option C. -> 61
:
C
Of all the 64 codons, three are known as termination codons or stop codons, which do not code for any amino acid. They are UAA, UAG and UGA. They act as stop signals for protein synthesis. Remaining 61 codons code for 20 known amino acids.
Question 2.


Semi-discontinuous mode of DNA replication was discovered by


  1.     Meselson and Stahl
  2.     Watson and Crick
  3.     Hershey and Chase
  4.     Okazaki and Okazaki
 Discuss Question
Answer: Option D. -> Okazaki and Okazaki
:
D

DNA replication is ‘semi-discontinuous’ because one of the strands is synthesised continuously, while the other strand, discontinuously by the formation of Okazaki fragments. This was discovered in the year 1968 by a Japanese scientist couple - Reiji Okazaki and his wife Tsuneko Okazaki. The term ‘Okazaki fragments’ has been given after them.


Question 3.


Watson and Crick constructed the double helical model of DNA based on images developed by Rosalind Franklin through _______________ technique.


  1.     X-ray diffraction
  2.     Autoradiography
  3.     Electrophoresis
  4.     Chromatography
 Discuss Question
Answer: Option A. -> X-ray diffraction
:
A

Rosalind Franklin, a young biophysicist, was working on the structure of DNA around the same time as Watson and Crick. While they initially came up with a triple helical structure, she already had a strong clue that DNA is a double helix, through the images that she had developed through X-ray diffraction. Unfortunately, she wasn’t alive to share the Nobel Prize with them in the year 1962.


Question 4.


State whether true or false.


DNA from a single human cell measures about 2.2 cm in length.


  1.     True
  2.     False
  3.     Electrophoresis
  4.     Chromatography
 Discuss Question
Answer: Option B. -> False
:
B

DNA is a long molecule compactly arranged in the nucleus of the cell. When stretched out, the length of the DNA molecule from a single cell measures longer than the average height of a human being.


Question 5.


A bacteriophage is a type of


  1.     Bacteria that attack viruses
  2.     Fungus that attacks bacteria
  3.     Protozoan
  4.     Virus that infects bacteria
 Discuss Question
Answer: Option D. -> Virus that infects bacteria
:
D
A bacteriophage is a type of virus that infects bacteria. It acts as a medium of gene transfer among bacteria by the process called transduction (phage-mediated gene transfer).
Question 6.


A bacteriophage is a type of


  1.     Bacteria that attack viruses
  2.     Fungus that attacks bacteria
  3.     Protozoan
  4.     Virus that infects bacteria
 Discuss Question
Answer: Option D. -> Virus that infects bacteria
:
D
A bacteriophage is a type of virus that infects bacteria. It acts as a medium of gene transfer among bacteria by the process called transduction (phage-mediated gene transfer).
Question 7.


Semi-discontinuous mode of DNA replication was discovered by


  1.     Meselson and Stahl
  2.     Watson and Crick
  3.     Hershey and Chase
  4.     Okazaki and Okazaki
 Discuss Question
Answer: Option D. -> Okazaki and Okazaki
:
D

DNA replication is ‘semi-discontinuous’ because one of the strands is synthesised continuously, while the other strand, discontinuously by the formation of Okazaki fragments. This was discovered in the year 1968 by a Japanese scientist couple - Reiji Okazaki and his wife Tsuneko Okazaki. The term ‘Okazaki fragments’ has been given after them.


Question 8.


The Mutation Theory was put forward by


  1.     Francis Crick
  2.     James Watson
  3.     Hugo de Vries
  4.     Frederick Griffith
 Discuss Question
Answer: Option C. -> Hugo de Vries
:
C
Mutation was first observed by Hugo de Vries in 1886 while studying the evening primrose Oenothera lamarckiana. He noticed wild varieties of the plant that differed from the original cultivated species.
Question 9.


Regarding the assertion and reason, select the correct option:
Assertion [A]: Gene regulation involves turning on and off of genes as per the requirement of the cells.
Reason [R]: Gene expression and gene regulation mean the same.


  1.     Both A and R are true and R explains A
  2.     Both A and R are true, but R does not explain A
  3.     A is true and R is false
  4.     Both A and R are false
 Discuss Question
Answer: Option C. -> A is true and R is false
:
C
Gene expression results in the formation of a protein, and hence, involves both transcription and translation. This however, is controlled by various mechanisms in different organisms. The phenomenon by which expression of these genes is regulated is known as gene regulation. This basically means that gene regulation involves switching on or off of the genes.
Question 10.


Regarding the assertion and reason, select the correct option.
Assertion [A]: The template strand runs in the 3’-5’ direction.
Reason [R]: The genetic information resides on the sense strand.


  1.     Both A and R are true and R explains A
  2.     Both A and R are true, but R does not explain A
  3.     A is true and R is false
  4.     Both A and R are false
 Discuss Question
Answer: Option A. -> Both A and R are true and R explains A
:
A
During transcription, one of the two DNA strands of the double helix acts as a template for the synthesis of mRNA. This is known as the template strand or antisense strand, and runs along the 3’-5’ direction. The other DNA strand which runs in the 5’-3’ direction is known as the coding strand or sense strand. This appears exactly like the newly transcribed mRNA strand (except that ‘T’ and ‘U’ would differ respectively).

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