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Total Questions : 67 | Page 4 of 7 pages
Question 31. Which of the following enzyme is responsible for initiating DNA replication?
  1.    polymerase
  2.    ligase
  3.    primase
  4.    gyrase
 Discuss Question
Answer: Option C. -> primase
Answer: (c).primase
Question 32. How many pathways of nucleotide excision repair exist?
  1.    1
  2.    2
  3.    3
  4.    4
 Discuss Question
Answer: Option B. -> 2
Answer: (b).2
Question 33. Which repair system operates to repair DNA strands that are actively transcribed?
  1.    Double-strand breakage repair
  2.    Nucleotide excision repair
  3.    RNA repair
  4.    Messenger RNA repair
 Discuss Question
Answer: Option B. -> Nucleotide excision repair
Answer: (b).Nucleotide excision repair
Question 34. Xeroderma pigmentosum is caused by ______________________
  1.    UV radiations
  2.    X-rays
  3.    Gamma radiations
  4.    Beta-rays
 Discuss Question
Answer: Option A. -> UV radiations
Answer: (a).UV radiations
Question 35. A mismatched base pair can cause ________________ in the double helix.
  1.    change in geometry
  2.    change in location
  3.    change in size
  4.    change in alkalinity
 Discuss Question
Answer: Option A. -> change in geometry
Answer: (a).change in geometry
Question 36. The NHEJ pathway is used to rectify __________________ in the DNA.
  1.    nucleotide substitutions
  2.    double-strand breaks
  3.    single-strand breaks
  4.    mismatched basepairs
 Discuss Question
Answer: Option B. -> double-strand breaks
Answer: (b).double-strand breaks
Question 37. Which of the following does not introduce double-strand breaks in the DNA?
  1.    Gamma rays
  2.    Cancer drugs
  3.    Free radicals
  4.    Inherited mutations
 Discuss Question
Answer: Option D. -> Inherited mutations
Answer: (d).Inherited mutations
Question 38. Replicative polymerase Η belongs to a family of polymerases involved in ________________
  1.    translesion synthesis
  2.    mRNA localization
  3.    mRNA translation
  4.    mRNA stability
 Discuss Question
Answer: Option A. -> translesion synthesis
Answer: (a).translesion synthesis
Question 39. Which if the following polymerases have an unusually spacious active site?
  1.    DNA polymerases
  2.    TLS polymerases
  3.    RNA polymerases
  4.    DNA helicases
 Discuss Question
Answer: Option B. -> TLS polymerases
Answer: (b).TLS polymerases
Question 40. Which form of Xeroderma pigmentosum is observed in patients who cannot synthesize functional polymerase Η?
  1.    XP III
  2.    XP IV
  3.    XP V
  4.    XP VI
 Discuss Question
Answer: Option C. -> XP V
Answer: (c).XP V

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