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Total Questions : 137 | Page 7 of 14 pages
Question 61. Arrange the following sequences of tumor development in the correct order?
1) Metastasis
2) Progression
3) Promotion
4) Initiation
  1.    2, 3, 4, 1
  2.    4, 3, 2, 1
  3.    1, 2, 3, 4
  4.    1, 3, 4, 2
 Discuss Question
Answer: Option B. -> 4, 3, 2, 1
Answer: (b).4, 3, 2, 1
Question 62. Name the process of transition from normal cells to cancerous cells?
  1.    Ubiquitylation
  2.    Polymerization
  3.    Transformation
  4.    Metastasis
 Discuss Question
Answer: Option C. -> Transformation
Answer: (c).Transformation
Question 63. Which of the following is the characteristic of a cancer cell?
  1.    Density dependent inhibition
  2.    Contact inhibition
  3.    Loss of anchorage dependence
  4.    Apoptosis
 Discuss Question
Answer: Option C. -> Loss of anchorage dependence
Answer: (c).Loss of anchorage dependence
Question 64. Which of the following is NOT the example of proto-oncogenes?
  1.    Rb
  2.    Src
  3.    Myc
  4.    Abl
 Discuss Question
Answer: Option A. -> Rb
Answer: (a).Rb
Question 65. What is angiogenesis?
  1.    Differentiation process
  2.    Growth factors
  3.    Contact inhibition
  4.    Blood vessel formation
 Discuss Question
Answer: Option D. -> Blood vessel formation
Answer: (d).Blood vessel formation
Question 66. Which of the following mutation causes Burkitt’s lymphoma?
  1.    Point mutation
  2.    Chromosomal translocation
  3.    Deletion
  4.    Duplication
 Discuss Question
Answer: Option B. -> Chromosomal translocation
Answer: (b).Chromosomal translocation
Question 67. Name the genes which directly inhibit cell growth or promote cell death.
  1.    Gatekeeper genes
  2.    Caretaker genes
  3.    Checkpoints
  4.    Transcription factors
 Discuss Question
Answer: Option A. -> Gatekeeper genes
Answer: (a).Gatekeeper genes
Question 68. Name the chemical carcinogen which causes prostate cancer.
  1.    Radon
  2.    Arsenic
  3.    Cadmium
  4.    Asbestos
 Discuss Question
Answer: Option C. -> Cadmium
Answer: (c).Cadmium
Question 69. Which of the following chromosomal alteration causes retinoblastoma?
  1.    Deletion in chromosome 11
  2.    Translocation between chromosome 9 and 22
  3.    Deletion in chromosome 13
  4.    Translocation between chromosome 8 and 21
 Discuss Question
Answer: Option C. -> Deletion in chromosome 13
Answer: (c).Deletion in chromosome 13
Question 70. If DNA is damaged, which of the following gene arrest cell cycle?
  1.    Rb
  2.    p53
  3.    Hedgehog receptor
  4.    p16
 Discuss Question
Answer: Option B. -> p53
Answer: (b).p53

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