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MCQs

Total Questions : 179 | Page 6 of 18 pages
Question 51. Which of the following equations correct for Henderson-Hasselbach equation for weak acids?
  1.    PH = pKa – log (Unionized drug concentration /Ionized drug concentration)
  2.    PH = pKa – log (Ionized drug concentration/ Unionized drug concentration)
  3.    PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
  4.    PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
 Discuss Question
Answer: Option C. -> PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
Answer: (c).PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
Question 52. Which of the following equations correct for Henderson-Hasselbach equation for weak bases?
  1.    PH = pKa – log (Unionized drug concentration /Ionized drug concentration)
  2.    PH = pKa – log (Ionized drug concentration/ Unionized drug concentration)
  3.    PH = pKa + log (Ionized drug concentration/ Unionized drug concentration)
  4.    PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
 Discuss Question
Answer: Option D. -> PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
Answer: (d).PH = pKa + log (Unionized drug concentration /Ionized drug concentration)
Question 53. What is the pH range of the intestine?
  1.    4-5
  2.    1-3
  3.    1-8
  4.    5-8
 Discuss Question
Answer: Option D. -> 5-8
Answer: (d).5-8
Question 54. What is the pH range of the stomach?
  1.    1-4
  2.    5-8
  3.    1-3
  4.    1-8
 Discuss Question
Answer: Option C. -> 1-3
Answer: (c).1-3
Question 55. Acids in the pKa range 2.5-7.5 are greatly affected by changes in pH making their absorption pH dependent.
  1.    True
  2.    False
  3.    May be True or False
  4.    Can't say
 Discuss Question
Answer: Option A. -> True
Answer: (a).True
Question 56. Example of a drug which has PKa > 11 is ________
  1.    Cromolyn
  2.    Imipramine
  3.    Amitriptyline
  4.    Mecamylamine
 Discuss Question
Answer: Option D. -> Mecamylamine
Answer: (d).Mecamylamine
Question 57. What should be the range of oil/water partition coefficient of any drug?
  1.    1-2
  2.    3-4
  3.    2-3
  4.    1-3
 Discuss Question
Answer: Option A. -> 1-2
Answer: (a).1-2
Question 58. Which one of these is not an example of a basic drug with pKa range 5-11?
  1.    Cromolyn
  2.    Imipramine
  3.    Amitriptyline
  4.    Chloroquine
 Discuss Question
Answer: Option A. -> Cromolyn
Answer: (a).Cromolyn
Question 59. Which one of these is an example of a strong acid drug?
  1.    Diazepam
  2.    Ibuprofen
  3.    Cromolyn
  4.    Aspirin
 Discuss Question
Answer: Option C. -> Cromolyn
Answer: (c).Cromolyn
Question 60. Ibuprofen a weak acid, in the stomach will be present in which of the given form?
  1.    Ionized form mostly
  2.    Non-ionized form mostly
  3.    Half ionized and half no ionized
  4.    Will form aggregate
 Discuss Question
Answer: Option B. -> Non-ionized form mostly
Answer: (b).Non-ionized form mostly

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