Sail E0 Webinar
Question
X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be
Options:
A .  activation of B cells by T-independent antigens
B .  failure of B cells to provide co-stimulation for Th2 activation
C .  failure of Th2 cells to provide co-stimulation for B cell isotype switching
D .  failure of Th2 cells to provide co-stimulation for B cell proliferation
Answer: Option C
Answer: (c).failure of Th2 cells to provide co-stimulation for B cell isotype switching

Was this answer helpful ?
Next Question

Submit Solution

Your email address will not be published. Required fields are marked *

Latest Videos

Latest Test Papers