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Question
Which of the following is wrong statement about the maximum likelihood method’s steps?
Options:
A .  It starts with an evolutionary model of sequence change that provides estimates of rates of substitution of one base for another
B .  In the beginning there is an evolutionary model of sequence change that provides estimates of transitions and transversions in a set of nucleic acid sequences
C .  The rates of all possible substitutions are chosen so that the base composition differs
D .  The set of sequences is then aligned
Answer: Option C
Answer: (c).The rates of all possible substitutions are chosen so that the base composition differs

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