A method of sequence alignment based on a Model (Bishop and Thompson 1986) was i

Question

A method of sequence alignment based on a Model (Bishop and Thompson 1986) was introduced that predicts the manner in which DNA sequences change during evolution. Which of the following is wrong about it?

Options:

A . This method is different from the Smith-Waterman local alignment algorithm

B . This method is quite similar to the Smith-Waterman local alignment algorithm

C . The underlying mutational theory is like those used to produce the PAM matrices for predicting changes in DNA and protein sequences

D . Sequences are predicted to change by a Markov process such that each mutation in the sequence is independent of previous mutations at that site or at other sites

Answer: Option B
Answer: (b).This method is quite similar to the Smith-Waterman local alignment algorithm

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