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Question
Which of the following is not a drawback of the progressive alignment method?
Options:
A .  The progressive alignment method is not suitable for comparing sequences of different lengths because it is a global alignment–based method
B .  In this method the use of affine gap penalties, long gaps are not allowed, and, in some cases, this may limit the accuracy of the method
C .  In this method the use of affine gap penalties, long gaps is allowed, and, in some cases, this may limit the accuracy of the method
D .  The final alignment result is also influenced by the order of sequence addition
Answer: Option C
Answer: (c).In this method the use of affine gap penalties, long gaps is allowed, and, in some cases, this may limit the accuracy of the method

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