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Match the following
Column IColumn IIA. Humulini. Possesses 21 amino acids.B. A-peptideii. Extra stretch present in pro-insulin.C. B-peptideiii. First genetically engineered hormone.D. C-peptideiv. Connects peptide chains.E. Disulphide Bondsv. Possesses 30 amino acids.
Options:
A .  A-v, B-iv, C-iii, D-ii, E-i
B .  A- iii, B-i, C-v, D-ii, E-iv
C .  A-ii, B-iv,C-i,D-iii,E-v
D .  A-iv, B-iii, C-ii, D-i, E-v
Answer: Option B
:
B
Humulin is the first genetically engineered hormone that was approved for human use. Insulin contains two polypeptide chains A peptide and B peptide. The 'A' peptide is made of 21 amino acids while the 'B' peptide is made of 30 amino acids. Insulin contains three disulphide bonds- two between A and B peptides and one within the A peptide. The C - peptide is present in pro-insulin connecting the A and B peptides. This is cleaved to form active insulin.

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