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MCQs

Total Questions : 43 | Page 3 of 5 pages
Question 21.  The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as
  1.    transformation of antigen specific B lymphocytes (EBV)
  2.    hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
  3.    combination of EB Vand hybridoma techniques
  4.    all of these
 Discuss Question
Answer: Option D. -> all of these
Question 22.  Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with
  1.    Ig MAbs
  2.    IgG
  3.    IgA
  4.    IgE
 Discuss Question
Answer: Option A. -> Ig MAbs
Question 23.  In human B cells and T cells are matured in the
  1.    bone marrow and thymus respectively
  2.    bone marrow and thymus respectively
  3.    bursa and thymus respectively
  4.    none of these
 Discuss Question
Answer: Option A. -> bone marrow and thymus respectively
Question 24.  
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the
  1.    absence of human immune response against murine proteins (HAMA) response
  2.    presence of HAMA response
  3.    poor recognition of immunoglobulin, Ig constant regions
  4.    all of the above
 Discuss Question
Answer: Option A. -> absence of human immune response against murine proteins (HAMA) response
Question 25.  
In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a
  1.    hybridoma
  2.    myeloma
  3.    natural killer cell
  4.    lymphoblast
 Discuss Question
Answer: Option A. -> hybridoma
Question 26.  The cross linkage of antigens by antibodies is known as
  1.    A. agglutination
  2.    complement fixation
  3.    a cross reaction
  4.    all of these
 Discuss Question
Answer: Option A. -> A. agglutination
Question 27.  An example of mosaic antigen is
  1.    virus
  2.    bacteria
  3.    a hapten
  4.    protein
 Discuss Question
Answer: Option A. -> virus
Question 28.  T cells are the source of
  1.    interleukin
  2.    interferon
  3.    lymphotoxin
  4.    all of these
 Discuss Question
Answer: Option D. -> all of these
Question 29. . In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,
  1.    T8 cells are greatly reduced
  2.    T8 cells are greatly increased
  3.    T4 cells are greatly reduced
  4.    T4 cells are greatly increased
 Discuss Question
Answer: Option A. -> T8 cells are greatly reduced
Question 30. . Helper T cells assist in the functions of
  1.    certain B cells
  2.    certain T cells
  3.    certain B cells and other T cells
  4.    none of the above
 Discuss Question
Answer: Option C. -> certain B cells and other T cells

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