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MCQs

Total Questions : 43 | Page 1 of 5 pages
Question 1. The cross linkage of antigens by antibodies is known as
  1.    all of these
  2.    agglutination
  3.    complement fixation
  4.    a cross reaction
 Discuss Question
Answer: Option B. -> agglutination
Question 2. Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with
  1.    IgA
  2.    IgE
  3.    IgG
  4.    Ig MAbs
 Discuss Question
Answer: Option D. -> Ig MAbs
Question 3. In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a
  1.    lymphoblast
  2.    natural killer cell
  3.    myeloma
  4.    hybridoma
 Discuss Question
Answer: Option D. -> hybridoma
Question 4. The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as
  1.    all of these
  2.    combination of EB Vand hybridoma techniques
  3.    transformation of antigen specific B lymphocytes (EBV)
  4.    hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
 Discuss Question
Answer: Option A. -> all of these
Question 5. Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the
  1.    absence of human immune response against murine proteins (HAMA) response
  2.    poor recognition of immunoglobulin, Ig constant regions
  3.    All of these
  4.    presence of HAMA response
 Discuss Question
Answer: Option A. -> absence of human immune response against murine proteins (HAMA) response
Question 6. The primary B cell receptor is
  1.    IgG
  2.    IgD
  3.    IgE
  4.    IgA
 Discuss Question
Answer: Option B. -> IgD
Question 7. T cells are the source of
  1.    lymphotoxin
  2.    all of these
  3.    interleukin
  4.    interferon
 Discuss Question
Answer: Option B. -> all of these
Question 8. An example of mosaic antigen is
  1.    protein
  2.    a hapten
  3.    virus
  4.    bacteria
 Discuss Question
Answer: Option C. -> virus
Question 9. In human B cells and T cells are matured in the
  1.    bursa and thymus respectively
  2.    lymph nodes and spleen respectively
  3.    bone marrow and thymus respectively
  4.    none of these
 Discuss Question
Answer: Option C. -> bone marrow and thymus respectively
Question 10. It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at
  1.    low frequencies
  2.    moderate frequencies
  3.    at no frequency
  4.    high frequencies
 Discuss Question
Answer: Option D. -> high frequencies

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