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MCQs

Total Questions : 108 | Page 5 of 11 pages
Question 41. . Which histone(s) are associated with the linker DNA of a nucleosome?
  1.    Histone H1
  2.    Histones H2A and H2B
  3.    Histone H3
  4.    Histone H4
 Discuss Question
Answer: Option A. -> Histone H1
Question 42. . DNA can be sequenced by the
  1.    chemical method
  2.    chain termination procedure
  3.    both (a) and (b)
  4.    physical method
 Discuss Question
Answer: Option C. -> both (a) and (b)
Question 43. . In a cesium chloride gradient, DNA labeled with 15N and centrifuged will form a band
  1.    above DNA containing 14N
  2.    below DNA containing 14N
  3.    with 14N-containing DNA
  4.    all of these
 Discuss Question
Answer: Option B. -> below DNA containing 14N
Question 44. . Deoxyribonucleoside triphosphates, being need in the chain termination methods are
  1.    dATP
  2.    dGTP and dCTP
  3.    dTTP
  4.    all of these
 Discuss Question
Answer: Option D. -> all of these
Question 45. . The role of primase is to
  1.    dismantle RNA primer
  2.    cleave and unwinds short sections of DNA ahead of the replication fork
  3.    proofread base pairing
  4.    synthesize an RNA primer to begin the elongation process
 Discuss Question
Answer: Option D. -> synthesize an RNA primer to begin the elongation process
Question 46. . What is the approximate percentage of repetitive DNA sequences in human DNA?
  1.    10 to 20%
  2.    20 to 30%
  3.    30 to 40%
  4.    40 to 50%
 Discuss Question
Answer: Option B. -> 20 to 30%
Question 47. . The packing ratio of nucleosomes is about
  1.    6
  2.    8
  3.    7
  4.    9
 Discuss Question
Answer: Option C. -> 7
Question 48. . The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?
  1.    AZT (zidovudine) is too expensive to be taken in effective doses
  2.    The RNase H domain of p66 causes error prone synthesis
  3.    It lacks a proofreading exonuclease
  4.    It has low affinity for the correct dNTP's
 Discuss Question
Answer: Option C. -> It lacks a proofreading exonuclease
Question 49. . 
The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by
  1.    using enzyme called telomerase
  2.    shortening of the double stranded replicated portion
  3.    using RNA as a template
  4.    none of the above
 Discuss Question
Answer: Option A. -> using enzyme called telomerase
Question 50. . 
After one replication in 15N, how many bands should be observed in a cesium chloride gradient?
  1.    One
  2.    Two
  3.    Three
  4.    A smear
 Discuss Question
Answer: Option A. -> One

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