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MCQs

Total Questions : 115 | Page 6 of 12 pages
Question 51. Nude mice refers to
  1.    mice without skin
  2.    mice without thymus
  3.    knockout mice
  4.    transgenic mice
 Discuss Question
Answer: Option B. -> mice without thymus


-NA-


Question 52. A humanized antibody is one in which the
  1.    heavy and light chains are from human
  2.    heavy chain is from human and light chain is from mouse
  3.    light chain is from human and heavy chain is from mouse
  4.    CDRs are from mouse, and the rest is from human
 Discuss Question
Answer: Option D. -> CDRs are from mouse, and the rest is from human


-NA-


Question 53. Dimethyl sulfoxide (DMSO) is used as a cryopreservant for mammalian cell cultures because
  1.    it is an organic solvent
  2.    it easily penetrates cells
  3.    it protects cells by preventing crystallization of water
  4.    it is also utilized as a nutrient
 Discuss Question
Answer: Option C. -> it protects cells by preventing crystallization of water


-NA-


Question 54. Choose the correct signal transduction pathway.
  1.    Hormone → 7 TM receptor → G protein → cAMP → PKA
  2.    Hormone → G protein → 7 TM receptor → cAMP → PKA
  3.    Hormone → 7 TM receptor → G protein → PKA → cAMP
  4.    Hormone → 7 TM receptor → cAMP → G protein → PKA
 Discuss Question
Answer: Option A. -> Hormone → 7 TM receptor → G protein → cAMP → PKA


-NA-


Question 55. Heat inactivation of serum is done to inactivate
  1.    prions
  2.    mycoplasma
  3.    complement
  4.    pathogenic bacteria
 Discuss Question
Answer: Option C. -> complement


-NA-


Question 56. A truncated polypeptide is synthesized due to a nonsense mutation. Where would you introduce
another mutation to obtain a full-length polypeptide?
  1.    Ribosomal protein gene
  2.    Transfer RNA gene
  3.    DNA repair gene
  4.    Ribosomal RNA gene
 Discuss Question
Answer: Option B. -> Transfer RNA gene


-NA-


Question 57. A protein is phosphorylated at a serine residue. A phosphomimic mutant of the protein can be
generated by substituting that serine with
  1.    glycine
  2.    alanine
  3.    aspartate
  4.    threonine
 Discuss Question
Answer: Option C. -> aspartate


-NA-


Question 58. Protein-DNA interactions in vivo can be studied by
  1.    gel shift assay
  2.    Southern hybridization
  3.    chromatin immunoprecipitation assay
  4.    fluorescence in situ hybridization assay
 Discuss Question
Answer: Option C. -> chromatin immunoprecipitation assay


-NA-


Question 59. The direction of shell coiling in the snail Limnaea peregra is a classic example of
  1.    chromosomal inheritance
  2.    extra-chromosomal inheritance
  3.    chromosomal translocation
  4.    homologous recombination
 Discuss Question
Answer: Option B. -> extra-chromosomal inheritance


-NA-


Question 60. During photorespiration under low CO2 and high O2 levels, O2 reacts with ribulose
1,5- bisphosphate to yield
  1.    one molecule each of 3-phosphoglycerate and 2-phosphoglycolate
  2.    two molecules of 3-phosphoglycerate
  3.    two molecules of 2-phosphoglycolate
  4.    one molecule each of 3-phosphoglycerate and glyoxylate
 Discuss Question
Answer: Option A. -> one molecule each of 3-phosphoglycerate and 2-phosphoglycolate


-NA-


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