Questions and answers for exam Preparation

MCQs

Total Questions : 61 | Page 2 of 7 pages

Question 11. Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 12. If the bioavailability of test formulation is 80-120% of the reference standard, it is considered to be bioequivalent.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 13. Bioequivalence is a relative term which denotes that the drug substance reaches the systemic circulation at the same relative rate or time.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 14. A drug with poor stability means higher bioavailability.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option B. -> False
Answer: (b).False

Question 15. Poor bioavailability means poor aqueous solubility.

True
False
May be True or False
Can't say

Discuss Question

Answer: Option A. -> True
Answer: (a).True

Question 16. Which of the following is not an approach for overcoming bioavailability problems?

Pharmaceutic approach
Pharmacokinetic approach
Biologic approach
Partition coefficient approach

Discuss Question

Answer: Option D. -> Partition coefficient approach
Answer: (d).Partition coefficient approach

Question 17. What does the word “open” mean in the one compartment open model?

The drug easily enters
The drug readily mixes with the blood
Unidirectional input and output
Easy absorption

Discuss Question

Answer: Option C. -> Unidirectional input and output
Answer: (c).Unidirectional input and output

Question 18. What is meant by elimination half-life?

Time take for half of the amount of drug to get completely eliminated from only the organs
Time take for half of the amount of drug to get completely eliminated from only blood
Time take for half of the amount of drug to get completely eliminated from only plasma
Time take for half of the amount of drug to get completely eliminated from the body as well as plasma

Discuss Question

Answer: Option D. -> Time take for half of the amount of drug to get completely eliminated from the body as well as plasma
Answer: (d).Time take for half of the amount of drug to get completely eliminated from the body as well as plasma

Question 19. What is the equation to find out the apparent volume of distribution?

Amount of drug in the body/plasma drug concentration
Plasma drug concentration/amount of drug in the body
1 / plasma drug concentration
1 / Amount of drug in the body

Discuss Question

Answer: Option A. -> Amount of drug in the body/plasma drug concentration
Answer: (a).Amount of drug in the body/plasma drug concentration

Question 20. In the equation log C = log Co – KEt/2.303, what does Co stand for _______

Plasma drug concentration after 60 min of i.v. injection
Plasma drug concentration after 15 min of i.v. injection
Plasma drug concentration after 30 min of i.v. injection
Plasma drug concentration immediately after i.v. injection

Discuss Question

Answer: Option D. -> Plasma drug concentration immediately after i.v. injection
Answer: (d).Plasma drug concentration immediately after i.v. injection