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MCQs

Total Questions : 119 | Page 8 of 12 pages
Question 71. Bone marrow given to an infant with SCID must
  1.    be irradiated to eliminate GVHD
  2.    contain mature T cells that can begin making immune responses immediately
  3.    come from a donor that shares some MHC alleles with the recipient
  4.    come from one of the child's parents
 Discuss Question
Answer: Option C. -> come from a donor that shares some MHC alleles with the recipient
Answer: (c).come from a donor that shares some MHC alleles with the recipient
Question 72. X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be
  1.    activation of B cells by T-independent antigens
  2.    failure of B cells to provide co-stimulation for Th2 activation
  3.    failure of Th2 cells to provide co-stimulation for B cell isotype switching
  4.    failure of Th2 cells to provide co-stimulation for B cell proliferation
 Discuss Question
Answer: Option C. -> failure of Th2 cells to provide co-stimulation for B cell isotype switching
Answer: (c).failure of Th2 cells to provide co-stimulation for B cell isotype switching
Question 73. The HIV virus infects primarily
  1.    brain cells
  2.    cells in the immune system
  3.    red blood cells
  4.    liver cells
 Discuss Question
Answer: Option B. -> cells in the immune system
Answer: (b).cells in the immune system
Question 74. Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with
  1.    CTL killing of viruses
  2.    dendritic cell activation to become a mature APC
  3.    infected cell processing of virus peptides
  4.    macrophage intracellular killing of bacteria
 Discuss Question
Answer: Option D. -> macrophage intracellular killing of bacteria
Answer: (d).macrophage intracellular killing of bacteria
Question 75. Difficulties with somatic gene therapy arise from all of the following except
  1.    GVHD caused by mature T cells in the transplanted cells
  2.    inserting a gene so that it will function properly
  3.    limited life span of more mature hematopoietic cells
  4.    transducing genetic material into stem cells
 Discuss Question
Answer: Option A. -> GVHD caused by mature T cells in the transplanted cells
Answer: (a).GVHD caused by mature T cells in the transplanted cells
Question 76. The chemical, typically released by the body in an allergic response is
  1.    histamine
  2.    allergens
  3.    antihistamines
  4.    perforins
 Discuss Question
Answer: Option A. -> histamine
Answer: (a).histamine
Question 77. The protein, produced by B cells that binds to a specific antigen is
  1.    phagocyte
  2.    leukocyte
  3.    vaccine
  4.    antibody
 Discuss Question
Answer: Option D. -> antibody
Answer: (d).antibody
Question 78. What type of B cell is like a tiny factory that produces antibodies identical to the B cell receptor that bind to the original antigen?
  1.    T cells
  2.    Memory cells
  3.    Plasma cells
  4.    Macrophages
 Discuss Question
Answer: Option C. -> Plasma cells
Answer: (c).Plasma cells
Question 79. Which of the following blood proteins can destroy pathogens?
  1.    Major histocompatibility complex
  2.    Platelets
  3.    Fibrinogen
  4.    Complement system
 Discuss Question
Answer: Option D. -> Complement system
Answer: (d).Complement system
Question 80. Which of the following characteristics are common in lymphocytes, macrophages, and neutrophils?
  1.    They are all part of the nonspecific immune response in vertebrates
  2.    They are all part of the specific immune response in vertebrates
  3.    They are all part of the internal defenses of nonvertebrates
  4.    They are all types of white blood cells
 Discuss Question
Answer: Option D. -> They are all types of white blood cells
Answer: (d).They are all types of white blood cells

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